Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 3/20 | 0.47 |
| ▸ | CTSS | P25774 | 3/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | CDC25B | P30305 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALPG | P10696 | 1/20 | 0.46 |
| ▸ | PAM | P19021 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21635721 | 0.86 | ALDH1A1 (0.50) | ALDH1A1MAPK1L3MBTL1TDP1SLC6A2 | |
| SCHEMBL11584476 | 0.85 | TDP1 (0.49) | ALDH1A1MAPK1L3MBTL1TDP1SLC6A2 | |
| SCHEMBL9862907 | 0.83 | MMP1 (0.53) | ALDH1A1MAPK1L3MBTL1TDP1LMNA | |
| SCHEMBL43748 | 0.83 | ALDH1A1 (0.63) | ALDH1A1MAPK1L3MBTL1TDP1SLC6A2 | |
| SCHEMBL9098710 | 0.83 | ALDH1A1 (0.63) | ALDH1A1MAPK1L3MBTL1TDP1SLC6A2 | |
| SCHEMBL17107936 | 0.82 | ALDH1A1 (0.50) | ALDH1A1MAPK1L3MBTL1TDP1SLC6A2 | |
| SCHEMBL20523795 | 0.82 | CYP19A1 (0.44) | ALDH1A1MAPK1L3MBTL1TDP1KMT2A | |
| SCHEMBL20523786 | 0.82 | KMT2A (0.45) | ALDH1A1MAPK1L3MBTL1KMT2ALMNA | |
| SCHEMBL3321151 | 0.82 | TDP1 (0.58) | ALDH1A1MAPK1L3MBTL1TDP1KMT2A | |
| SCHEMBL11522867 | 0.82 | MAPT (0.48) | ALDH1A1MAPK1L3MBTL1TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 359 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12351541-B2 | Process for preparing cyanoacetates | HENKEL AG & CO. KGAA (DE) | 2025-07-08 | — | — | US | claimed |
| CN-115151527-B | Process for the preparation of cyanoacetic esters | 汉高股份有限及两合公司 | 2025-05-13 | — | — | CN | claimed |
| EP-3956297-B1 | PROCESS FOR PREPARING CYANOACETATES | HENKEL AG & CO KGAA (DE) | 2024-09-04 | — | — | EP | claimed |
| EP-3956293-B1 | PROCESS FOR PREPARING CYANOACETATES | HENKEL AG & CO KGAA (DE) | 2024-08-07 | — | — | EP | claimed |
| CN-118421037-A | Preparation method and application of high-stability green perovskite quantum dot polymer particles | 北京航空航天大学合肥创新研究院 | 2024-08-02 | — | — | CN | claimed |
| US-11976024-B2 | Process for preparing cyanoacetates | HENKEL AG & CO. KGAA (DE) | 2024-05-07 | — | — | US | claimed |
| US-11827584-B2 | Process for preparing cyanoacetates | HENKEL AG & CO. KGAA (DE) | 2023-11-28 | — | — | US | claimed |
| CN-116621732-A | 2-cyano-2-valproate and preparation method and application thereof | 湖南大学 | 2023-08-22 | — | — | CN | claimed |
| EP-4073030-A1 | PROCESS FOR PREPARING CYANOACETATES | Henkel AG & Co. KGaA (DE) | 2022-10-19 | — | — | EP | claimed |
| US-20220315526-A1 | PROCESS FOR PREPARING CYANOACETATES | HENKEL IRELAND OPERATIONS AND RESEARCH LIMITED (IE) | 2022-10-06 | — | — | US | claimed |
| WO-2020212583-A1 | PROCESS FOR PREPARING CYANOACETATES | Henkel IP & Holding GmbH (DE) | 2020-10-22 | — | — | WO | claimed |
| WO-2020212585-A1 | PROCESS FOR PREPARING CYANOACETATES | Henkel IP & Holding GmbH (DE) | 2020-10-22 | — | — | WO | claimed |
| CN-109422656-A | The synthetic method of nonamethylene diamine | 北京旭阳科技有限公司 | 2019-03-05 | — | — | CN | claimed |
| CN-104945316-B | A kind of method of microwave method synthesis 2- halos nicotinate and its intermediate | 山东师范大学 | 2018-05-04 | — | — | CN | claimed |
| CN-104945317-A | Method for synthesizing 2-halogenated ester nicotinate and 2-halogenated ester nicotinate intermediate according to ultrasonic method | UNIV SHANDONG NORMAL | 2015-09-30 | — | — | CN | claimed |
| CN-104945316-A | Method for synthesizing 2-halogenated nicotinic acid ester and intermediates thereof through microwave method | UNIV SHANDONG NORMAL | 2015-09-30 | — | — | CN | claimed |
| CN-102786436-B | A kind of method of synthesizing cyanoacetate | ZHEJIANG JIURJIU CHEMICALS CO., LTD. (CN) | 2015-09-16 | — | — | CN | claimed |
| CN-102863326-A | Preparation method of antiepileptic drug intermediate | Changzhou pharmaceutical factory co ltd | 2013-01-09 | — | — | CN | claimed |
| CN-102786436-A | Method for synthesizing cyanoacetate | ZHEJIANG JIURJIU CHEMICALS CO LTD | 2012-11-21 | — | — | CN | claimed |
| WO-1999043650-A2 | PROCESS(ES) FOR THE PREPARATION OF 6-TRIFLUOROMETHYL-INDOLINE DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 1999-09-02 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11827584-B2 | Process for preparing cyanoacetates | PCCA, DNPEP, ASNS | ALDH1A1 2035/4885MAPK1 3202/4885L3MBTL1 4481/4885 |
| US-20220315526-A1 | PROCESS FOR PREPARING CYANOACETATES | PCCA, ACMSD, AADAT | ALDH1A1 595/4885MAPK1 1414/4885L3MBTL1 4424/4885 |
| US-12351541-B2 | Process for preparing cyanoacetates | PCCA, CPS1, COASY | ALDH1A1 1346/4885MAPK1 3012/4885L3MBTL1 4571/4885 |
| US-11976024-B2 | Process for preparing cyanoacetates | PCCA, ACMSD, AADAT | ALDH1A1 595/4885MAPK1 1414/4885L3MBTL1 4424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.