SCHEMBL3321151

SCHEMBL3321151

N#CCC(=O)OCCc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.58
APP P05067 1/20 0.50
HCAR2 Q8TDS4 1/20 0.50
ESR1 P03372 1/20 0.49
ESR2 Q92731 1/20 0.49
ALOX5 P09917 2/20 0.48
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
ALDH1A1 P00352 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
AKR1B10 O60218 2/20 0.47
AKR1B1 P15121 2/20 0.47
TP53 P04637 1/20 0.47
GLA P06280 1/20 0.47
CYP3A4 P08684 1/20 0.47
HPGD P15428 1/20 0.47
TSHR P16473 1/20 0.47
MAPK1 P28482 1/20 0.47
HIF1A Q16665 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11525182 0.90 LMNA (0.58) TDP1NPC1RAB9AALDH1A1SMN1; SMN2
Tetrahydrofuran SCHEMBL28781827 0.89 ALDH1A1 (0.50) TDP1APPHCAR2ESR1ESR2
SCHEMBL11584476 0.85 TDP1 (0.49) TDP1ESR1ESR2L3MBTL1ALDH1A1
SCHEMBL16672946 0.84 TDP1 (0.59) TDP1APPHCAR2ESR1ESR2
SCHEMBL11589414 0.83 CTDSP1 (0.44) TDP1APPRAB9AL3MBTL1KMT2A
SCHEMBL10900628 0.83 THRB (0.54) TDP1NPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL187996 0.82 ALDH1A1 (0.61) TDP1HCAR2L3MBTL1ALDH1A1MAPK1
SCHEMBL6123744 0.81 MAPT (0.54) TDP1NPC1RAB9AL3MBTL1ALDH1A1
SCHEMBL451184 0.80 TDP1 (0.68) TDP1APPHCAR2ESR1ESR2
SCHEMBL22832718 0.80 TDP1 (0.81) TDP1APPHCAR2ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12351541-B2 Process for preparing cyanoacetates HENKEL AG & CO. KGAA (DE) 2025-07-08 US claimed
CN-115151527-B Process for the preparation of cyanoacetic esters 汉高股份有限及两合公司 2025-05-13 CN claimed
EP-3956297-B1 PROCESS FOR PREPARING CYANOACETATES HENKEL AG & CO KGAA (DE) 2024-09-04 EP claimed
EP-3956293-B1 PROCESS FOR PREPARING CYANOACETATES HENKEL AG & CO KGAA (DE) 2024-08-07 EP claimed
US-11976024-B2 Process for preparing cyanoacetates HENKEL AG & CO. KGAA (DE) 2024-05-07 US claimed
US-11827584-B2 Process for preparing cyanoacetates HENKEL AG & CO. KGAA (DE) 2023-11-28 US claimed
EP-4073030-A1 PROCESS FOR PREPARING CYANOACETATES Henkel AG & Co. KGaA (DE) 2022-10-19 EP claimed
US-20220315526-A1 PROCESS FOR PREPARING CYANOACETATES HENKEL IRELAND OPERATIONS AND RESEARCH LIMITED (IE) 2022-10-06 US claimed
EP-3956298-A1 PROCESS FOR PREPARING CYANOACETATES Henkel IP & Holding GmbH (DE) 2022-02-23 EP claimed
EP-3956297-A1 PROCESS FOR PREPARING CYANOACETATES Henkel IP & Holding GmbH (DE) 2022-02-23 EP claimed
EP-3956293-A1 PROCESS FOR PREPARING CYANOACETATES Henkel IP & Holding GmbH (DE) 2022-02-23 EP claimed
US-20220033350-A1 PROCESS FOR PREPARING CYANOACETATES HENKEL IRELAND OPERATIONS AND RESEARCH LIMITED (IE) 2022-02-03 US claimed
US-20220033353-A1 PROCESS FOR PREPARING CYANOACETATES HENKEL IRELAND OPERATIONS AND RESEARCH LIMITED (IE) 2022-02-03 US claimed
US-20220033349-A1 PROCESS FOR PREPARING CYANOACETATES HENKEL AG & CO. KGAA (DE) 2022-02-03 US claimed
CN-113710646-A Process for preparing cyanoacetic acid esters 汉高知识产权控股有限责任公司 2021-11-26 CN claimed
WO-2021116128-A1 PROCESS FOR PREPARING CYANOACETATES Henkel IP & Holding GmbH (DE) 2021-06-17 WO claimed
WO-2020212585-A1 PROCESS FOR PREPARING CYANOACETATES Henkel IP & Holding GmbH (DE) 2020-10-22 WO claimed
WO-2020212583-A1 PROCESS FOR PREPARING CYANOACETATES Henkel IP & Holding GmbH (DE) 2020-10-22 WO claimed
WO-2020212584-A1 PROCESS FOR PREPARING CYANOACETATES Henkel IP & Holding GmbH (DE) 2020-10-22 WO claimed
US-12351541-B2 Process for preparing cyanoacetates HENKEL AG & CO. KGAA (DE) 2025-07-08 US disclosed
US-12351540-B2 Process for preparing cyanoacetates HENKEL AG & CO. KGAA (DE) 2025-07-08 US disclosed
CN-115151527-B Process for the preparation of cyanoacetic esters 汉高股份有限及两合公司 2025-05-13 CN disclosed
EP-4532465-A1 BIOBASED CYANOACRYLATE COMPOUND Bostik SA (FR) 2025-04-09 EP disclosed
CN-119451941-A Bio-based cyanoacrylate compounds 博斯蒂克股份公司 2025-02-14 CN disclosed
EP-3956297-B1 PROCESS FOR PREPARING CYANOACETATES HENKEL AG & CO KGAA (DE) 2024-09-04 EP disclosed
EP-3956293-B1 PROCESS FOR PREPARING CYANOACETATES HENKEL AG & CO KGAA (DE) 2024-08-07 EP disclosed
US-11976024-B2 Process for preparing cyanoacetates HENKEL AG & CO. KGAA (DE) 2024-05-07 US disclosed
US-11827584-B2 Process for preparing cyanoacetates HENKEL AG & CO. KGAA (DE) 2023-11-28 US disclosed
CN-110114337-B Method for preparing electron-deficient olefins 汉高股份有限及两合公司 2023-05-30 CN disclosed
EP-4073030-A1 PROCESS FOR PREPARING CYANOACETATES Henkel AG & Co. KGaA (DE) 2022-10-19 EP disclosed
US-20220315526-A1 PROCESS FOR PREPARING CYANOACETATES HENKEL IRELAND OPERATIONS AND RESEARCH LIMITED (IE) 2022-10-06 US disclosed
EP-3956297-A1 PROCESS FOR PREPARING CYANOACETATES Henkel IP & Holding GmbH (DE) 2022-02-23 EP disclosed
EP-3956293-A1 PROCESS FOR PREPARING CYANOACETATES Henkel IP & Holding GmbH (DE) 2022-02-23 EP disclosed
EP-3956298-A1 PROCESS FOR PREPARING CYANOACETATES Henkel IP & Holding GmbH (DE) 2022-02-23 EP disclosed
US-20220033350-A1 PROCESS FOR PREPARING CYANOACETATES HENKEL IRELAND OPERATIONS AND RESEARCH LIMITED (IE) 2022-02-03 US disclosed
US-20220033349-A1 PROCESS FOR PREPARING CYANOACETATES HENKEL AG & CO. KGAA (DE) 2022-02-03 US disclosed
US-20220033353-A1 PROCESS FOR PREPARING CYANOACETATES HENKEL IRELAND OPERATIONS AND RESEARCH LIMITED (IE) 2022-02-03 US disclosed
CN-113710647-A Process for preparing cyanoacetic acid esters 汉高知识产权控股有限责任公司 2021-11-26 CN disclosed
CN-113710646-A Process for preparing cyanoacetic acid esters 汉高知识产权控股有限责任公司 2021-11-26 CN disclosed
CN-113692400-A Process for preparing cyanoacetic acid esters 汉高知识产权控股有限责任公司 2021-11-23 CN disclosed
WO-2021116128-A1 PROCESS FOR PREPARING CYANOACETATES Henkel IP & Holding GmbH (DE) 2021-06-17 WO disclosed
WO-2020212584-A1 PROCESS FOR PREPARING CYANOACETATES Henkel IP & Holding GmbH (DE) 2020-10-22 WO disclosed
WO-2020212585-A1 PROCESS FOR PREPARING CYANOACETATES Henkel IP & Holding GmbH (DE) 2020-10-22 WO disclosed
WO-2020212583-A1 PROCESS FOR PREPARING CYANOACETATES Henkel IP & Holding GmbH (DE) 2020-10-22 WO disclosed
CN-110167912-A The method for preparing electron deficient olefins precursor 汉高知识产权控股有限责任公司 2019-08-23 CN disclosed
US-8674125-B2 Method for the preparation of phosphine butadiene ligands, complexes thereof with copper and use thereof in catalysis CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2014-03-18 US disclosed
US-20130165667-A1 METHOD FOR THE PREPARATION OF PHOSPHINE BUTADIENE LIGANDS, COMPLEXES THEREOF WITH COPPER AND USE THEREOF IN CATALYSIS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2013-06-27 US disclosed
US-20100121076-A1 METHOD FOR THE PREPARATION OF PHOSPHINE BUTADIENE LIGANDS, COMPLEXES THEREOF WITH COPPER AND USE THEREOF IN CATALYSIS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2010-05-13 US disclosed
US-5935563-A SUNSCREEN AGENT; 3,5-DIALKYL SUBSTITUTED 4-HYDROXYBENZYLIDENECYANOACETATE DERIVATIVE USED AS A COSMETIC BASF AKTIENGESELLSCHAFT (DE) 1999-08-10 US disclosed
EP-0339671-B1 Derivative of caffeic acid and pharmaceutical composition containing the same SUNTORY LTD (JP) 1994-08-10 EP disclosed
US-5063243-A Arteriosclerosis treatment SUNTORY, LTD. (JP) 1991-11-05 US disclosed
EP-0339671-A2 Derivative of caffeic acid and pharmaceutical composition containing the same SUNTORY LIMITED (JP) 1989-11-02 EP disclosed
US-4172944-A Water insoluble styryl dyestuffs having hetero-aryl methylene substituent BAYER AKTIENGESELLSCHAFT (DE) 1979-10-30 US disclosed
US-4105665-A MONOMETHINE DYESTUFFS BAYER AKTIENGESELLSCHAFT (DE) 1978-08-08 US disclosed
US-4088673-A Process for the preparation of styryl dyestuffs BAYER AKTIENGESELLSCHAFT (DT) 1978-05-09 US disclosed
US-4077962-A WATER INSOLUBLE, GREEN-YELLOW, SYNTHETIC FIBERS BAYER AKTIENGESELLSCHAFT (DT) 1978-03-07 US disclosed
US-4046771-A GREENISH-YELLOW SHADES ON SYNTHETIC FIBERS BAYER AKTIENGESELLSCHAFT (DT) 1977-09-06 US disclosed
US-4018796-A FIBERS BAYER AKTIENGESELLSCHAFT (DT) 1977-04-19 US disclosed
US-4016191-A WATER INSOLUBLE; LIGHTFASTNESS BAYER AKTIENGESELLSCHAFT (DT) 1977-04-05 US disclosed
US-4016172-A DYEING POLYAMIDES AND POLYURETHANES BAYER AKTIENGESELLSCHAFT (DT) 1977-04-05 US disclosed
US-3959306-A Azolindolines and azolindoline dyestuffs BAYER AKTIENGESELLSCHAFT (DT) 1976-05-25 US disclosed
US-3959306-A Azolindolines and azolindoline dyestuffs BAYER AKTIENGESELLSCHAFT (DT) 1976-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130165667-A1 METHOD FOR THE PREPARATION OF PHOSPHINE BUTADIENE LIGANDS, COMPLEXES THEREOF WITH COPPER AND USE THEREOF IN CATALYSIS BCHE, DOHH, AOC1 TDP1 3711/4885APP 3254/4885HCAR2 3800/4885
US-20220033349-A1 PROCESS FOR PREPARING CYANOACETATES PCCA, DNPEP, ASNS TDP1 3018/4885APP 1149/4885HCAR2 541/4885
US-20220033353-A1 PROCESS FOR PREPARING CYANOACETATES PCCA, CPS1, COASY TDP1 3596/4885APP 2337/4885HCAR2 605/4885
US-11827584-B2 Process for preparing cyanoacetates PCCA, DNPEP, ASNS TDP1 3018/4885APP 1149/4885HCAR2 541/4885
US-12351540-B2 Process for preparing cyanoacetates ASNS, PCCA, NANS TDP1 3808/4885APP 1442/4885HCAR2 2494/4885
US-20220033350-A1 PROCESS FOR PREPARING CYANOACETATES ASNS, PCCA, NANS TDP1 3808/4885APP 1442/4885HCAR2 2494/4885
US-20220315526-A1 PROCESS FOR PREPARING CYANOACETATES PCCA, ACMSD, AADAT TDP1 3102/4885APP 3146/4885HCAR2 51/4885
US-20100121076-A1 METHOD FOR THE PREPARATION OF PHOSPHINE BUTADIENE LIGANDS, COMPLEXES THEREOF WITH COPPER AND USE THEREOF IN CATALYSIS PDXK, AOC1, PNPO TDP1 3753/4885APP 2428/4885HCAR2 4718/4885
US-12351541-B2 Process for preparing cyanoacetates PCCA, CPS1, COASY TDP1 3596/4885APP 2337/4885HCAR2 605/4885
US-11976024-B2 Process for preparing cyanoacetates PCCA, ACMSD, AADAT TDP1 3102/4885APP 3146/4885HCAR2 51/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.