Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 4/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.35 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.35 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.35 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.35 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.35 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.35 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18801188 | 0.89 | L3MBTL1 (0.41) | METAP2L3MBTL1LMNAKDM4ENPC1 | |
| SCHEMBL18801306 | 0.81 | METAP2 (0.56) | METAP2ALDH1A1HPGDL3MBTL1TUBB4A | |
| SCHEMBL1649281 | 0.80 | METAP2 (0.48) | METAP2ALDH1A1HPGDTUBB4ATUBB | |
| SCHEMBL18801179 | 0.79 | LMNA (0.45) | ALOX5ALDH1A1HPGDL3MBTL1LMNA | |
| SCHEMBL18801494 | 0.78 | L3MBTL1 (0.40) | METAP2ALDH1A1HPGDL3MBTL1LMNA | |
| SCHEMBL1648250 | 0.78 | METAP2 (0.43) | METAP2L3MBTL1TUBB4ATUBBTUBA3C | |
| SCHEMBL18801500 | 0.74 | ALDH1A1 (0.39) | ALOX5ALDH1A1HPGDL3MBTL1LMNA | |
| SCHEMBL18801318 | 0.73 | METAP2 (0.43) | METAP2ALDH1A1TUBB4ATUBBTUBA3C | |
| SCHEMBL18801445 | 0.72 | MTNR1A (0.40) | METAP2ALDH1A1L3MBTL1TUBB4ATUBB | |
| SCHEMBL1648290 | 0.72 | METAP2 (0.39) | METAP2HPGDKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2486004-B1 | SULPHONE COMPOUNDS FOR USE IN THE TREATMENT OF OBESITY | ZAFGEN INC (US) | 2017-05-03 | — | — | EP | disclosed |