Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | METAP2 | P50579 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18801192 | 0.87 | METAP2 (0.34) | NPSR1SMN1; SMN2L3MBTL1METAP2MAPT | |
| SCHEMBL18801177 | 0.84 | MEN1 (0.36) | NPSR1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL18801342 | 0.84 | ALDH1A1 (0.36) | NPSR1SMN1; SMN2L3MBTL1MAPTMEN1 | |
| SCHEMBL18801182 | 0.82 | MEN1 (0.39) | NPSR1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL18801468 | 0.80 | LMNA (0.37) | SMN1; SMN2L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL18801127 | 0.78 | MEN1 (0.36) | NPSR1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL1648199 | 0.76 | ALOX5 (0.36) | NPSR1SMN1; SMN2L3MBTL1MAPTMEN1 | |
| SCHEMBL18801069 | 0.75 | KDM4E (0.32) | NPSR1KDM4EGAALMNAHPGD | |
| SCHEMBL436712 | 0.75 | METAP2 (0.41) | NPSR1SMN1; SMN2METAP2MAPTMEN1 | |
| SCHEMBL18801337 | 0.74 | SMN1; SMN2 (0.37) | NPSR1SMN1; SMN2L3MBTL1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2486004-B1 | SULPHONE COMPOUNDS FOR USE IN THE TREATMENT OF OBESITY | ZAFGEN INC (US) | 2017-05-03 | — | — | EP | disclosed |