SCHEMBL1880935

SCHEMBL1880935

CC[C@@H](C(=O)OC)N1CCCC1=O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.69
CA12 O43570 1/20 0.69
CA1 P00915 1/20 0.69
CA2 P00918 1/20 0.69
CA3 P07451 1/20 0.69
CA4 P22748 1/20 0.69
CA6 P23280 1/20 0.69
CA5A P35218 1/20 0.69
CA7 P43166 1/20 0.69
CA9 Q16790 1/20 0.69
CA13 Q8N1Q1 1/20 0.69
CA14 Q9ULX7 1/20 0.69
CA5B Q9Y2D0 1/20 0.69
CHRM2 P08172 1/20 0.37
CHRM4 P08173 1/20 0.37
CHRM5 P08912 1/20 0.37
CHRM1 P11229 1/20 0.37
CHRM3 P20309 1/20 0.37
ALDH1A1 P00352 1/20 0.36
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3789746 1.00 LMNA (0.69) LMNACA12CA1CA2CA3
SCHEMBL3789749 1.00 LMNA (0.69) LMNACA12CA1CA2CA3
SCHEMBL15723483 0.88 LMNA (0.56) LMNACA12CA1CA2CA3
SCHEMBL21313417 0.87 LMNA (0.69) LMNACA12CA1CA2CA3
SCHEMBL1878246 0.87 LMNA (0.69) LMNACA12CA1CA2CA3
SCHEMBL8353244 0.87 LMNA (0.69) LMNACA12CA1CA2CA3
SCHEMBL13911898 0.86 LMNA (0.71) LMNACA12CA1CA2CA3
SCHEMBL4445759 0.83 LMNA (0.63) LMNACA12CA1CA2CA3
SCHEMBL14610554 0.82 LMNA (0.50) LMNACA12CA1CA2CA3
SCHEMBL5101967 0.82 LMNA (0.50) LMNACA12CA1CA2CA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115260075-A Method for preparing levetiracetam 浙江华海药业股份有限公司 2022-11-01 CN claimed
CN-114409586-A Preparation method of levetiracetam 山东诚汇双达药业有限公司 2022-04-29 CN claimed
WO-2024206349-A1 PROCESS FOR THE PRODUCTION OF LEVETIRACETAM SUZHOU BRIGHTHOPE PHARMATECH CO., LTD (CN) 2024-10-03 WO disclosed
CN-110799494-B Method for preparing levetiracetam without solvent 浙江华海药业股份有限公司 2023-06-06 CN disclosed
CN-110799495-B Synthesis method of levetiracetam 浙江华海药业股份有限公司 2022-12-13 CN disclosed
CN-108707099-B Preparation method of levetiracetam intermediate 浙江华海药业股份有限公司 2022-12-13 CN disclosed
CN-115260075-A Method for preparing levetiracetam 浙江华海药业股份有限公司 2022-11-01 CN disclosed
US-20220162165-A1 PREPARATION METHOD FOR LEVETIRACETAM INTERMEDIATE ZHEJIANG HUAHAI TIANCHENG PHARMACEUTICAL CO., LTD (CN) 2022-05-26 US disclosed
CN-114409586-A Preparation method of levetiracetam 山东诚汇双达药业有限公司 2022-04-29 CN disclosed
WO-2020216146-A1 PREPARATION METHOD FOR LEVETIRACETAM INTERMEDIATE 浙江华海药业股份有限公司 2020-10-29 WO disclosed
US-8338621-B2 Process for the preparation of 2-oxo-1-pyrrolidine derivatives UCB S.A. (BE) 2012-12-25 US disclosed
WO-2008077035-A2 PROCESSES FOR THE PREPARATION OF LEVETIRACETAM DR. REDDY'S LABORATORIES LTD. (IN) 2008-06-26 WO disclosed
US-20080146819-A1 Process for Preparing Levetiracetam RUBAMIN LIMITED (IN) 2008-06-19 US disclosed
US-20080146819-A1 Process for Preparing Levetiracetam RUBAMIN LIMITED (IN) 2008-06-19 US disclosed
WO-2008012268-A1 PROCESS FOR THE PREPARATION OF LEVETIRACETAM ZACH SYSTEM S.P.A. (IT) 2008-01-31 WO disclosed
US-20080009638-A1 PROCESS FOR THE PREPARATION OF 2-OXO-1-PYRROLIDINE DERIVATIVES UCB S.A. (BE) 2008-01-10 US disclosed
EP-1806339-A1 Process for the preparation of 2-oxo-1-pyrrolidine derivatives UCB, S.A. (BE) 2007-07-11 EP disclosed
US-20070142647-A1 Oxopyrrolidine compounds, preparation of said compounds and their use in the manufacturing of levetiracetam and analogues ATES CELAL 2007-06-21 US disclosed
US-20070142647-A1 Oxopyrrolidine compounds, preparation of said compounds and their use in the manufacturing of levetiracetam and analogues ATES CELAL 2007-06-21 US disclosed
WO-2003014080-A2 OXOPYRROLIDINE COMPOUNDS, PREPARATION OF SAID COMPOUNDS AND THEIR USE IN THE MANUFACTURING OF LEVETIRACETAM AND ANALOGUES UCB, S.A. (BE) 2003-02-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080009638-A1 PROCESS FOR THE PREPARATION OF 2-OXO-1-PYRROLIDINE DERIVATIVES CYP2F1, CYP3A5, SULT1E1 LMNA 4186/4885CA12 3778/4885CA1 2079/4885
US-20080146819-A1 Process for Preparing Levetiracetam ADH1C, ADH1A, ADH5 LMNA 3024/4885CA12 810/4885CA1 124/4885
US-20220162165-A1 PREPARATION METHOD FOR LEVETIRACETAM INTERMEDIATE ADRM1, GABRE, EPM2A LMNA 2136/4885CA12 4446/4885CA1 2825/4885
US-20070142647-A1 Oxopyrrolidine compounds, preparation of said compounds and their use in the manufacturing of levetiracetam and analogues CYP2D6, OTC, CYP2B6 LMNA 2327/4885CA12 2417/4885CA1 1400/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.