Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18816129 | 0.99 | ALDH1A1 (0.44) | ALDH1A1ENPP2MAPK1NPC1MAPT | |
| SCHEMBL28103733 | 0.90 | ATM (0.45) | ALDH1A1ENPP2MAPTTDP1KMT2A | |
| SCHEMBL14185148 | 0.85 | ALDH1A1 (0.50) | ALDH1A1MAPK1NPC1MAPTRAB9A | |
| SCHEMBL1126961 | 0.82 | ALDH1A1 (0.48) | ALDH1A1MAPK1NPC1MAPTRAB9A | |
| SCHEMBL1126964 | 0.82 | ALDH1A1 (0.48) | ALDH1A1MAPK1NPC1MAPTRAB9A | |
| SCHEMBL18816151 | 0.79 | HSD17B10 (0.50) | ALDH1A1MAPK1NPC1MAPTRAB9A | |
| SCHEMBL18842342 | 0.79 | HSD17B10 (0.50) | ALDH1A1MAPK1NPC1MAPTRAB9A | |
| SCHEMBL18816134 | 0.78 | HSD17B10 (0.49) | ALDH1A1MAPK1NPC1MAPTRAB9A | |
| SCHEMBL8968649 | 0.77 | ALDH1A1 (0.53) | ALDH1A1MAPK1NPC1MAPTRAB9A | |
| SCHEMBL8968657 | 0.77 | ALDH1A1 (0.53) | ALDH1A1MAPK1NPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106232572-B | The manufacturing method of nitro compound | 住友化学株式会社 | 2018-11-13 | — | — | CN | disclosed |
| US-9975844-B2 | Method for producing nitro compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-05-22 | — | — | US | disclosed |
| CN-106164041-B | The manufacture method of nitro compound | 住友化学株式会社 | 2018-05-04 | — | — | CN | disclosed |
| US-9822061-B2 | Method for producing nitro compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-11-21 | — | — | US | disclosed |
| US-20170144961-A1 | METHOD FOR PRODUCING NITRO COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-05-25 | — | — | US | disclosed |
| US-20170129846-A1 | METHOD FOR PRODUCING NITRO COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-05-11 | — | — | US | disclosed |
| CN-106232572-A | The manufacture method of nitro compound | 住友化学株式会社 | 2016-12-14 | — | — | CN | disclosed |
| CN-106164041-A | The manufacture method of nitro compound | 住友化学株式会社 | 2016-11-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170144961-A1 | METHOD FOR PRODUCING NITRO COMPOUND | NOS2, CYP11B2, NOS1 | ALDH1A1 345/4885ENPP2 3047/4885MAPK1 636/4885 |
| US-20170129846-A1 | METHOD FOR PRODUCING NITRO COMPOUND | NOX1, NOS1, NOX3 | ALDH1A1 451/4885ENPP2 4488/4885MAPK1 1409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.