Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18842342 | 1.00 | HSD17B10 (0.50) | HSD17B10SMN1; SMN2TSHRALDH1A1TDP1 | |
| SCHEMBL18816134 | 0.99 | HSD17B10 (0.49) | HSD17B10SMN1; SMN2TSHRALDH1A1TDP1 | |
| SCHEMBL14185148 | 0.89 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1TDP1KMT2AHTT | |
| SCHEMBL28103719 | 0.89 | MAPT (0.46) | HSD17B10SMN1; SMN2TSHRALDH1A1TDP1 | |
| SCHEMBL18816155 | 0.83 | SIGMAR1 (0.45) | SMN1; SMN2TSHRALDH1A1TDP1KMT2A | |
| SCHEMBL1126961 | 0.82 | ALDH1A1 (0.48) | SMN1; SMN2ALDH1A1TDP1KMT2AHTT | |
| SCHEMBL1126964 | 0.82 | ALDH1A1 (0.48) | SMN1; SMN2ALDH1A1TDP1KMT2AHTT | |
| SCHEMBL25286798 | 0.82 | ALDH1A1 (0.43) | HSD17B10SMN1; SMN2ALDH1A1TDP1KMT2A | |
| SCHEMBL18816133 | 0.82 | ALDH1A1 (0.45) | SMN1; SMN2TSHRALDH1A1TDP1KMT2A | |
| SCHEMBL25286797 | 0.82 | ALDH1A1 (0.43) | HSD17B10SMN1; SMN2ALDH1A1TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106232572-B | The manufacturing method of nitro compound | 住友化学株式会社 | 2018-11-13 | — | — | CN | disclosed |
| US-9975844-B2 | Method for producing nitro compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-05-22 | — | — | US | disclosed |
| CN-106164041-B | The manufacture method of nitro compound | 住友化学株式会社 | 2018-05-04 | — | — | CN | disclosed |
| US-9822061-B2 | Method for producing nitro compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-11-21 | — | — | US | disclosed |
| US-20170144961-A1 | METHOD FOR PRODUCING NITRO COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-05-25 | — | — | US | disclosed |
| US-20170129846-A1 | METHOD FOR PRODUCING NITRO COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-05-11 | — | — | US | disclosed |
| CN-106232572-A | The manufacture method of nitro compound | 住友化学株式会社 | 2016-12-14 | — | — | CN | disclosed |
| CN-106164041-A | The manufacture method of nitro compound | 住友化学株式会社 | 2016-11-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170144961-A1 | METHOD FOR PRODUCING NITRO COMPOUND | NOS2, CYP11B2, NOS1 | HSD17B10 252/4885SMN1; SMN2 2762/4885TSHR 2561/4885 |
| US-20170129846-A1 | METHOD FOR PRODUCING NITRO COMPOUND | NOX1, NOS1, NOX3 | HSD17B10 879/4885SMN1; SMN2 3073/4885TSHR 413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.