Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | LIPE | Q05469 | 1/20 | 0.35 |
| ▸ | TTK | P33981 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 2/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26828248 | 0.81 | TTK (0.35) | MEN1KMT2APAX8TTKGPR119 | |
| SCHEMBL7665673 | 0.79 | PAX8 (0.45) | MEN1KMT2APAX8LIPERXRA | |
| SCHEMBL20037705 | 0.79 | TTK (0.39) | MEN1KMT2APAX8LIPETTK | |
| SCHEMBL26757669 | 0.78 | TTK (0.35) | PAX8TTKGPR119PDK2 | |
| SCHEMBL31399702 | 0.78 | TTK (0.35) | PAX8TTKGPR119PDK2 | |
| SCHEMBL1181429 | 0.77 | GBA1 (0.42) | MEN1KMT2APAX8TTKGPR119 | |
| SCHEMBL29827507 | 0.77 | GBA1 (0.42) | MEN1KMT2APAX8TTKGPR119 | |
| SCHEMBL56808 | 0.77 | TTK (0.37) | PAX8TTKNR1H2GPR119RAB9A | |
| SCHEMBL989173 | 0.77 | TTK (0.37) | PAX8TTKGPR119TRPV1 | |
| SCHEMBL11968939 | 0.77 | GABRG2 (0.38) | PAX8TTKGPR119TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108430986-B | Fused bicyclic heterocyclic derivatives as pest control agents | 拜耳作物科学股份公司 | 2021-08-31 | — | — | CN | disclosed |
| US-10550116-B2 | Fused bicyclic heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-02-04 | — | — | US | disclosed |
| US-10550116-B2 | Fused bicyclic heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-02-04 | — | — | US | disclosed |
| US-20180305353-A1 | FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-10-25 | — | — | US | disclosed |
| EP-3368521-A1 | CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PEST CONTROL AGENTS | Bayer CropScience Aktiengesellschaft (DE) | 2018-09-05 | — | — | EP | disclosed |
| WO-2017072039-A1 | CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180305353-A1 | FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | DDT, BCHE, ACHE | MEN1 1507/4885KMT2A 1708/4885GRIN2B 860/4885 |
| US-10550116-B2 | Fused bicyclic heterocycle derivatives as pesticides | DDT, BCHE, ACHE | MEN1 1507/4885KMT2A 1708/4885GRIN2B 860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.