Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.67 |
| ▸ | CA9 | Q16790 | 2/20 | 0.67 |
| ▸ | CA2 | P00918 | 6/20 | 0.67 |
| ▸ | CA1 | P00915 | 5/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 8/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | GLA | P06280 | 4/20 | 0.64 |
| ▸ | GAA | P10253 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | ATM | Q13315 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.64 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.64 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.64 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18826373 | 0.90 | L3MBTL1 (0.55) | CA12CA9CA2CA1L3MBTL1 | |
| SCHEMBL18826376 | 0.85 | CA1 (0.91) | CA12CA9CA2CA1L3MBTL1 | |
| SCHEMBL18827580 | 0.83 | L3MBTL1 (0.82) | CA12CA9CA2CA1L3MBTL1 | |
| SCHEMBL18826377 | 0.78 | L3MBTL1 (1.00) | CA12CA9CA2CA1L3MBTL1 | |
| SCHEMBL14484122 | 0.77 | CA1 (1.00) | CA12CA9CA2CA1L3MBTL1 | |
| SCHEMBL18826390 | 0.76 | CA12 (0.80) | CA12CA9CA2CA1L3MBTL1 | |
| SCHEMBL18826382 | 0.75 | L3MBTL1 (0.84) | CA12CA9CA2CA1L3MBTL1 | |
| SCHEMBL18826380 | 0.75 | PTGS2 (0.80) | CA12CA9CA2CA1L3MBTL1 | |
| SCHEMBL27954385 | 0.74 | CA2 (0.76) | CA12CA9CA2CA1L3MBTL1 | |
| SCHEMBL18826375 | 0.74 | CA1 (0.91) | CA12CA9CA2CA1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9642835-B2 | Modulators of GTPase and use in relevant treatment | STC.UNM (US) | 2017-05-09 | — | — | US | disclosed |