Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 11/20 | 0.76 |
| ▸ | CA1 | P00915 | 9/20 | 0.76 |
| ▸ | CA12 | O43570 | 2/20 | 0.73 |
| ▸ | CA9 | Q16790 | 2/20 | 0.73 |
| ▸ | MMP2 | P08253 | 5/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | GLA | P06280 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.67 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.67 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28810693 | 0.91 | L3MBTL1 (0.79) | CA2CA1CA12CA9MMP2 | |
| SCHEMBL27955195 | 0.86 | EGFR (0.71) | CA2CA1MMP2GAAMEN1 | |
| SCHEMBL18826376 | 0.84 | CA1 (0.91) | CA2CA1CA12CA9MMP2 | |
| SCHEMBL27944763 | 0.84 | L3MBTL1 (0.69) | CA2CA1CA12CA9MMP2 | |
| SCHEMBL27954382 | 0.80 | MMP2 (0.77) | CA2CA1CA12CA9MMP2 | |
| SCHEMBL28808747 | 0.79 | MMP2 (0.81) | CA2CA1MMP2L3MBTL1KDM4E | |
| SCHEMBL14484122 | 0.77 | CA1 (1.00) | CA2CA1CA12CA9MMP2 | |
| SCHEMBL18826377 | 0.77 | L3MBTL1 (1.00) | CA2CA1CA12CA9MMP2 | |
| SCHEMBL18826384 | 0.74 | CA12 (0.67) | CA2CA1CA12CA9MMP2 | |
| SCHEMBL27955192 | 0.74 | EGFR (0.58) | CA2CA1CA12CA9MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103664786-A | Synthesis method of dihydro-pyrazole sulfonamide derivatives of salicylaldehydes and application of dihydro-pyrazole sulfonamide derivatives to preparation of anticancer drugs | NANJING UNIVERSITY OF TECHNOLOGY | 2014-03-26 | — | — | CN | disclosed |