Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL480202 | 0.98 | GAA (0.42) | GAAHTTRAB9ASMN1; SMN2TP53 | |
| SCHEMBL7698684 | 0.80 | KMT2A (0.40) | GAAHTTRAB9ASMN1; SMN2TP53 | |
| SCHEMBL6324391 | 0.78 | GAA (0.43) | GAAHTTRAB9ASMN1; SMN2TP53 | |
| SCHEMBL5406500 | 0.77 | GAA (0.52) | GAAHTTRAB9ASMN1; SMN2KMT2A | |
| SCHEMBL4630170 | 0.76 | KMT2A (0.47) | GAAHTTRAB9ASMN1; SMN2TP53 | |
| SCHEMBL9184806 | 0.76 | GAA (0.48) | GAAHTTRAB9ASMN1; SMN2HPGD | |
| SCHEMBL1882976 | 0.76 | GAA (0.48) | GAAHTTRAB9ASMN1; SMN2HPGD | |
| SCHEMBL10475080 | 0.75 | ALDH1A1 (0.45) | GAAHTTRAB9ASMN1; SMN2TP53 | |
| SCHEMBL47339 | 0.74 | KMT2A (0.46) | GAAHTTRAB9ASMN1; SMN2KMT2A | |
| SCHEMBL22179999 | 0.72 | F2 (0.50) | GAAHTTRAB9ASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028829-A2 | PEPTIDE DEFORMYLASE INHIBITORS | QUESTCOR PHARMACEUTICALS, INC. (US) | 2002-04-11 | — | — | WO | claimed |