Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | TERT | O14746 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | S100B | P04271 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9939716 | 0.81 | ALDH1A1 (0.46) | MAPTALDH1A1TSHRALOX15HSD17B10 | |
| SCHEMBL11037394 | 0.80 | ALDH1A1 (0.50) | MAPTALDH1A1TSHRALOX15HSD17B10 | |
| SCHEMBL19009077 | 0.79 | S1PR1 (0.46) | MAPTALDH1A1CYP3A4S1PR1S100B | |
| SCHEMBL346399 | 0.77 | ALDH1A1 (0.53) | MAPTALDH1A1TSHRALOX15HSD17B10 | |
| SCHEMBL29442599 | 0.76 | S100B (0.61) | MAPTALDH1A1TSHRALOX15HSD17B10 | |
| SCHEMBL33872 | 0.76 | S100B (0.61) | MAPTALDH1A1TSHRALOX15HSD17B10 | |
| SCHEMBL19075248 | 0.76 | ALDH1A1 (0.39) | MAPTALDH1A1TSHRCYP3A4TDP1 | |
| SCHEMBL21233548 | 0.76 | ALDH1A1 (0.39) | MAPTALDH1A1TSHRCYP3A4TDP1 | |
| SCHEMBL28523030 | 0.76 | S1PR1 (0.37) | ALDH1A1CYP3A4S1PR1S100BMEN1 | |
| SCHEMBL12156934 | 0.76 | S100B (0.37) | MAPTALDH1A1HSD17B10CYP3A4S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022109492-A1 | PYRROLOPYRIDAZINE COMPOUNDS AS KINASE INHIBITORS | GOSSAMER BIOSERVICES, INC. (US) | 2022-05-27 | — | — | WO | disclosed |
| US-9758688-B2 | Composition for forming conductive film | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-09-12 | — | — | US | disclosed |
| EP-2759543-B1 | CHROMENE COMPOUND AND CURABLE COMPOSITION | TOKUYAMA CORP (JP) | 2017-07-19 | — | — | EP | disclosed |
| US-20170174639-A1 | EIS INHIBITORS | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2017-06-22 | — | — | US | disclosed |
| US-9340529-B2 | Triazolones as fatty acid synthase inhibitors | GLAXOSMITHKLINE LLC (US) | 2016-05-17 | — | — | US | disclosed |
| US-20150275015-A1 | COMPOSITION FOR FORMING CONDUCTIVE FILM | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-10-01 | — | — | US | disclosed |
| EP-2699575-B1 | TRIAZOLOPYRIDINES | BAYER IP GMBH (DE) | 2015-03-25 | — | — | EP | disclosed |
| US-8916071-B2 | Chromene compound and curable composition | TOKUYAMA CORPORATION (JP) | 2014-12-23 | — | — | US | disclosed |
| US-20140225050-A1 | CHROMENE COMPOUND AND CURABLE COMPOSITION | TOKUYAMA CORPORATION (JP) | 2014-08-14 | — | — | US | disclosed |
| US-8802864-B2 | Triazolones as fatty acid synthase inhibitors | GLAXOSMITHKLINE LLC (US) | 2014-08-12 | — | — | US | disclosed |
| US-20120316151-A1 | TRIAZOLONES AS FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC | 2012-12-13 | — | — | US | disclosed |
| WO-2012143329-A1 | TRIAZOLOPYRIDINES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2012-10-26 | — | — | WO | disclosed |
| US-20110229910-A1 | Fluorescent Substrates for Neurotransmitter Transporters | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-09-22 | — | — | US | disclosed |
| WO-2011103546-A1 | TRIAZOLONES AS FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2011-08-25 | — | — | WO | disclosed |
| US-7947255-B2 | Exposing cell or extract to 4-(4-(dimethylamino)phenyl)-1-methylpyridinium iodide; high speed screening; kits | VANDERBILT UNIVERSITY (US) | 2011-05-24 | — | — | US | disclosed |
| EP-1702962-B1 | Ink composition containing a photo-acid and a photo-base generator and processes using them | FUJIFILM CORP (JP) | 2008-12-24 | — | — | EP | disclosed |
| US-20080108102-A1 | FLUORESCENT SUBSTRATES FOR NEUROTRANSMITTER TRANSPORTERS | VANDERBILT UNIVERSITY | 2008-05-08 | — | — | US | disclosed |
| WO-2008021870-A1 | FLUORESCENT SUBSTRATES FOR NEUROTRANSMITTER TRANSPORTERS | VANDERBILT UNIVERSITY (US) | 2008-02-21 | — | — | WO | disclosed |
| US-5356893-A | Antidepressants, nervous system disorders | GLAXO GROUP LIMITED (GB) | 1994-10-18 | — | — | US | disclosed |
| EP-0533266-A1 | Benzanilide derivatives as 5-HT1D antagonists | GLAXO GROUP LIMITED (GB) | 1993-03-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170174639-A1 | EIS INHIBITORS | ABCC1, ATP5ME, ABCG2 | MAPT 3708/4885ALDH1A1 819/4885TSHR 3072/4885 |
| US-20120316151-A1 | TRIAZOLONES AS FATTY ACID SYNTHASE INHIBITORS | FASN, FADS1, FADS2 | MAPT 4609/4885ALDH1A1 410/4885TSHR 2319/4885 |
| US-20140225050-A1 | CHROMENE COMPOUND AND CURABLE COMPOSITION | CRY2, CRY1, CDYL | MAPT 2242/4885ALDH1A1 2550/4885TSHR 1651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.