Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TRPC5 | Q9UL62 | 3/20 | 0.34 |
| ▸ | TRPC4 | Q9UBN4 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | PDE5A | O76074 | 4/20 | 0.34 |
| ▸ | TRPC1 | P48995 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | TACR2 | P21452 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18834254 | 0.94 | TRPC4 (0.40) | P2RX3ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL19375436 | 0.91 | P2RX7 (0.35) | P2RX3TRPC5TRPC4KCNH2PDE5A | |
| SCHEMBL21499680 | 0.90 | P2RX3 (0.39) | P2RX3ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL19375600 | 0.89 | P2RX3 (0.34) | P2RX3TRPC5TRPC4KCNH2PDE5A | |
| SCHEMBL19505503 | 0.89 | TRPC4 (0.39) | P2RX3TRPC5TRPC4KCNH2TRPC1 | |
| SCHEMBL20432022 | 0.87 | TRPC4 (0.42) | P2RX3TRPC5TRPC4KCNH2TRPC1 | |
| SCHEMBL20432432 | 0.86 | PDE5A (0.37) | P2RX3ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL20432069 | 0.86 | TRPC5 (0.36) | P2RX3ALDH1A1TRPC5KCNH2TSHR | |
| SCHEMBL19375398 | 0.86 | P2RX3 (0.38) | P2RX3ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL18834945 | 0.85 | TRPC4 (0.39) | P2RX3HTTTRPC5TRPC4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B1 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-05-10 | — | — | EP | disclosed |