Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 10/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19374868 | 0.87 | P2RX3 (0.36) | P2RX3 | |
| SCHEMBL19375435 | 0.81 | P2RX3 (0.30) | P2RX3 | |
| SCHEMBL18834196 | 0.75 | ALDH1A1 (0.40) | — | |
| SCHEMBL16364003 | 0.74 | TRPC4 (0.41) | P2RX3 | |
| SCHEMBL16028126 | 0.72 | TRPC5 (0.54) | — | |
| SCHEMBL19375602 | 0.71 | ADORA3 (0.43) | — | |
| SCHEMBL18834221 | 0.70 | P2RX3 (0.40) | P2RX3 | |
| SCHEMBL18834275 | 0.68 | TP53 (0.37) | P2RX3 | |
| SCHEMBL16122939 | 0.66 | GRIN1 (0.43) | P2RX3 | |
| SCHEMBL18833575 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B1 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-05-10 | — | — | EP | disclosed |