Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | KDM4B | O94953 | 1/20 | 0.34 |
| ▸ | KDM5C | P41229 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18831147 | 0.88 | MC4R (0.44) | CHRM2SIRT2HRH3SCN8APRMT6 | |
| SCHEMBL18880300 | 0.82 | CHRM2 (0.42) | CHRM2SIRT2LMNAKDM4EKDM4A | |
| SCHEMBL16006938 | 0.78 | SIGMAR1 (0.54) | SIRT2ALDH1A1KDM4EKDM5B | |
| SCHEMBL6205124 | 0.77 | CHRM2 (0.72) | CHRM2SIRT2HRH3SCN8AALOX15 | |
| SCHEMBL23891936 | 0.75 | CYP1A2 (0.44) | HRH3PRMT6ALOX15LMNATAAR1 | |
| SCHEMBL12213655 | 0.75 | PRMT6 (0.46) | PRMT6EPHX2KDM4EADRB2PDCD1 | |
| SCHEMBL18880283 | 0.74 | PRMT6 (0.42) | HRH3PRMT6ALOX15LMNATAAR1 | |
| SCHEMBL14076165 | 0.74 | PRMT6 (0.42) | HRH3PRMT6ALOX15LMNATAAR1 | |
| SCHEMBL18860211 | 0.74 | KDM4A (0.41) | CHRM2SIRT2PRMT6ALOX15LMNA | |
| SCHEMBL21527214 | 0.72 | NOS3 (0.52) | HRH3PRMT6ALOX15LMNATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3170811-A1 | ETHYL PYRIDINE-4-CARBOXYLATE COMPOUND AS INHIBITOR OF HISTONE DEMETHYLASES | Gilead Sciences, Inc. (US) | 2017-05-24 | — | — | EP | disclosed |