SCHEMBL1886071

SCHEMBL1886071

CCCC(C#N)C(=O)O.S=C(S)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.40
SLC6A3 Q01959 1/20 0.40
POLB P06746 1/20 0.35
LMNA P02545 3/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
ALDH1A1 P00352 2/20 0.35
MAPK1 P28482 1/20 0.35
CES2 O00748 4/20 0.35
CES1 P23141 4/20 0.35
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA3 P07451 1/20 0.34
CA4 P22748 1/20 0.34
CA6 P23280 1/20 0.34
CA5A P35218 1/20 0.34
CA7 P43166 1/20 0.34
CA9 Q16790 1/20 0.34
CA13 Q8N1Q1 1/20 0.34
CA14 Q9ULX7 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiobenzoic Acid SCHEMBL1886069 0.88 CA12 (0.48) SLC6A2SLC6A3POLBLMNASMN1; SMN2
SCHEMBL28434636 0.86 GAA (0.39) POLBLMNAALDH1A1MAPK1CA12
Benzoyl Peroxide SCHEMBL28296758 0.81 LMNA (0.50) SLC6A2SLC6A3LMNASMN1; SMN2ALDH1A1
SCHEMBL10494055 0.78
SCHEMBL651947 0.78
SCHEMBL10494014 0.78
Propane SCHEMBL29178080 0.76 CHRM1 (0.46) SLC6A3MAPK1CA2HDAC1HDAC7
SCHEMBL27372501 0.76 CHRM1 (0.46) SLC6A3MAPK1CA2HDAC1HDAC7
SCHEMBL28958900 0.76 CHRM1 (0.46) SLC6A3MAPK1CA2PPARGPPARA
Ammonia Solution, Strong SCHEMBL27495500 0.76 CHRM1 (0.46) SLC6A3MAPK1CA2HDAC1HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12539650-B2 Method for making embedded hydrogel contact lenses ALCON INC. (CH) 2026-02-03 US claimed
EP-4514595-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2025-03-05 EP claimed
EP-4240578-B1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC (CH) 2024-12-18 EP claimed
US-11886045-B2 Method for making photochromic contact lenses ALCON INC. (CH) 2024-01-30 US claimed
WO-2023209570-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-11-02 WO claimed
US-20230339149-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-10-26 US claimed
EP-4240578-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES Alcon Inc. (CH) 2023-09-13 EP claimed
WO-2022097048-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC. (CH) 2022-05-12 WO claimed
US-20220137433-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC. (CH) 2022-05-05 US claimed
CN-103396503-B New zwitter-ionic polymer containing multiple phosphonic acid end groups, preparation method and application thereof UNIV ZHEJIANG 2015-05-13 CN claimed
CN-102604310-B Water-phase preparing method of silica-coating polymer nano particles UNIV TONGJI 2014-04-02 CN claimed
CN-103396503-A New zwitter-ionic polymer containing multiple phosphonic acid end groups, preparation method and application thereof UNIV ZHEJIANG 2013-11-20 CN claimed
CN-102604310-A Water-phase preparing method of silica-coating polymer nano particles UNIV TONGJI 2012-07-25 CN claimed
US-20260131506-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC (CH) 2026-05-14 US disclosed
US-12539650-B2 Method for making embedded hydrogel contact lenses ALCON INC. (CH) 2026-02-03 US disclosed
US-12458703-B2 Responsive elastic polymers and methods of making and using same PURDUE RESEARCH FOUNDATION (US) 2025-11-04 US disclosed
WO-2009061854-A2 MULTIFUNCTIONAL DEGRADABLE NANOPARTICLES WITH CONTROL OVER SIZE AND FUNCTIONALITIES VANDERBILT UNIVERSITY (US) 2009-05-14 WO disclosed
US-20080221043-A1 Guanidinium compounds for drug delivery VANDERBILT UNIVERSITY 2008-09-11 US disclosed
WO-2008058108-A2 CROSSLINKED POLYMER THE LUBRIZOL CORPORATION (US) 2008-05-15 WO disclosed
WO-2008024435-A2 DENDRITIC MOLECULAR INTRACELLULAR TRANSPORTERS AND METHODS OF MAKING AND USING SAME VANDERBILT UNIVERSITY (US) 2008-02-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12539650-B2 Method for making embedded hydrogel contact lenses INF2, CRYZ, CRYAA SLC6A2 4803/4885SLC6A3 4765/4885POLB 2361/4885
US-12458703-B2 Responsive elastic polymers and methods of making and using same CD44, HCAR3, HCAR1 SLC6A2 1648/4885SLC6A3 3297/4885POLB 4761/4885
US-20080221043-A1 Guanidinium compounds for drug delivery GMPS, GUCY1A1, GUCY1A2 SLC6A2 82/4885SLC6A3 119/4885POLB 3560/4885
US-20260131506-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES CRYZ, CRYAB, CRYAA SLC6A2 3284/4885SLC6A3 3001/4885POLB 4215/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.