SCHEMBL18868046

SCHEMBL18868046

c1ccc(-c2ccc3c4ccc5oc6ccccc6c5c4n(-c4nc(-c5ccccc5)nc(-c5ccccc5)n4)c3c2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 4/20 0.36
PLA2G4A P47712 4/20 0.36
GAA P10253 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
MAPT P10636 4/20 0.33
ALDH1A1 P00352 4/20 0.33
HPGD P15428 2/20 0.33
TSHR P16473 2/20 0.33
LIMK1 P53667 1/20 0.33
PLA2G10 O15496 1/20 0.33
PGR P06401 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
RXFP1 Q9HBX9 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
KDM4E B2RXH2 2/20 0.31
LMNA P02545 1/20 0.31
MAPK1 P28482 1/20 0.31
HSD17B10 Q99714 1/20 0.31
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16522987 0.93 MAPT (0.34) PLA2G2APLA2G4AGAAL3MBTL1MAPT
SCHEMBL16160471 0.93 MAPT (0.34) PLA2G2APLA2G4AGAAL3MBTL1MAPT
SCHEMBL18868053 0.92 PLA2G2A (0.34) PLA2G2APLA2G4AGAAL3MBTL1MAPT
SCHEMBL18561387 0.92 PLA2G2A (0.36) PLA2G2APLA2G4AGAAL3MBTL1MAPT
SCHEMBL27324115 0.92 PLA2G2A (0.38) PLA2G2APLA2G4AGAAL3MBTL1MAPT
SCHEMBL18868048 0.92 PLA2G2A (0.38) PLA2G2APLA2G4AGAAL3MBTL1MAPT
SCHEMBL24218113 0.91 KDM4E (0.38) L3MBTL1MAPTALDH1A1HPGDTSHR
SCHEMBL15625543 0.90 MAPT (0.36) L3MBTL1MAPTALDH1A1HPGDTSHR
SCHEMBL25660291 0.90 PLA2G2A (0.34) PLA2G2APLA2G4AGAAALDH1A1PLA2G10
SCHEMBL21018301 0.90 PLA2G2A (0.36) PLA2G2APLA2G4AGAAL3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11569452-B2 Organic light-emitting device SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-01-31 US disclosed
US-20200194681-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2020-06-18 US disclosed
US-10615348-B2 Organic light-emitting device SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-04-07 US disclosed
US-20190393424-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-12-26 US disclosed
US-20190157603-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-05-23 US disclosed
US-20170141323-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-05-18 US disclosed
US-20170141323-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11569452-B2 Organic light-emitting device CRY1, TRPA1, CRY2 PLA2G2A 4112/4885PLA2G4A 4231/4885GAA 277/4885
US-20190393424-A1 ORGANIC LIGHT-EMITTING DEVICE OR10J3, LIN28A, OR51E2 PLA2G2A 4089/4885PLA2G4A 4477/4885GAA 2836/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.