SCHEMBL18868048

SCHEMBL18868048

c1ccc(-c2ccc3c(c2)c2ccc4oc5ccccc5c4c2n3-c2nc(-c3ccccc3)nc(-c3ccccc3)n2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 4/20 0.38
PLA2G4A P47712 4/20 0.38
PLA2G10 O15496 1/20 0.34
PGR P06401 1/20 0.34
GAA P10253 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MAPT P10636 3/20 0.33
TSHR P16473 2/20 0.33
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
CASP3 P42574 1/20 0.33
SENP7 Q9BQF6 1/20 0.33
SENP6 Q9GZR1 1/20 0.33
PRKDC P78527 3/20 0.32
TBK1 Q9UHD2 1/20 0.32
PIM1 P11309 1/20 0.31
CSNK2A2 P19784 1/20 0.31
CSNK2B P67870 1/20 0.31
PIM3 Q86V86 1/20 0.31
PIM2 Q9P1W9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27324115 1.00 PLA2G2A (0.38) PLA2G2APLA2G4APLA2G10PGRGAA
SCHEMBL21965567 0.94 PLA2G2A (0.33) PLA2G2APLA2G4APLA2G10MAPTTSHR
SCHEMBL21965496 0.94 PLA2G2A (0.33) PLA2G2APLA2G4APLA2G10MAPTTSHR
SCHEMBL18561397 0.92 PLA2G2A (0.38) PLA2G2APLA2G4APLA2G10PGRGAA
SCHEMBL18868046 0.92 PLA2G2A (0.36) PLA2G2APLA2G4APLA2G10PGRGAA
SCHEMBL16160471 0.92 MAPT (0.34) PLA2G2APLA2G4APGRGAAL3MBTL1
SCHEMBL16522987 0.92 MAPT (0.34) PLA2G2APLA2G4APGRGAAL3MBTL1
SCHEMBL18868053 0.91 PLA2G2A (0.34) PLA2G2APLA2G4APLA2G10PGRGAA
SCHEMBL19849277 0.90 PLA2G2A (0.34) PLA2G2APLA2G4APLA2G10MAPTTSHR
SCHEMBL21018298 0.90 PLA2G2A (0.38) PLA2G2APLA2G4APLA2G10PGRGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11569452-B2 Organic light-emitting device SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-01-31 US disclosed
US-20200194681-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2020-06-18 US disclosed
US-10615348-B2 Organic light-emitting device SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-04-07 US disclosed
US-20190393424-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-12-26 US disclosed
US-20190157603-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-05-23 US disclosed
US-20170141323-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-05-18 US disclosed
US-20170141323-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11569452-B2 Organic light-emitting device CRY1, TRPA1, CRY2 PLA2G2A 4112/4885PLA2G4A 4231/4885PLA2G10 4653/4885
US-20190393424-A1 ORGANIC LIGHT-EMITTING DEVICE OR10J3, LIN28A, OR51E2 PLA2G2A 4089/4885PLA2G4A 4477/4885PLA2G10 4590/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.