SCHEMBL18868050

SCHEMBL18868050

c1ccc(-c2nc(-c3ccccc3)nc(-n3c4ccc(-n5c6ccccc6c6ccccc65)cc4c4ccc5oc6ccccc6c5c43)n2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAC2 P15153 1/20 0.33
RAC3 P60763 1/20 0.33
CDC42 P60953 1/20 0.33
RAC1 P63000 1/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
KDM4E B2RXH2 1/20 0.33
ATM Q13315 1/20 0.33
ALDH1A1 P00352 2/20 0.31
HPGD P15428 2/20 0.31
TSHR P16473 1/20 0.31
MAPT P10636 1/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
LMNA P02545 1/20 0.31
MEN1 O00255 1/20 0.30
POLB P06746 1/20 0.30
MAPK1 P28482 1/20 0.30
DUSP3 P51452 1/20 0.30
PTPN5 P54829 1/20 0.30
KMT2A Q03164 1/20 0.30
PTPN11 Q06124 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18868051 0.95 L3MBTL1 (0.33) L3MBTL1KDM4EATMALDH1A1HPGD
SCHEMBL18561386 0.94 L3MBTL1 (0.35) RAC2RAC3CDC42RAC1L3MBTL1
SCHEMBL24217117 0.92 KDM4E (0.31) RAC2RAC3CDC42RAC1L3MBTL1
SCHEMBL22192377 0.92 L3MBTL1 (0.38) L3MBTL1KDM4EATMALDH1A1HPGD
SCHEMBL26630475 0.92 KDM4E (0.33) RAC2RAC3CDC42RAC1L3MBTL1
SCHEMBL21965567 0.91 PLA2G2A (0.33) KDM4EALDH1A1HPGDTSHRMAPT
SCHEMBL21965496 0.91 PLA2G2A (0.33) KDM4EALDH1A1HPGDTSHRMAPT
SCHEMBL15625543 0.91 MAPT (0.36) L3MBTL1KDM4EATMALDH1A1HPGD
SCHEMBL22192390 0.91 KDM4E (0.38) L3MBTL1KDM4EATMALDH1A1HPGD
SCHEMBL21018296 0.91 KDM4E (0.32) RAC2RAC3CDC42RAC1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11569452-B2 Organic light-emitting device SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-01-31 US disclosed
US-20200194681-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2020-06-18 US disclosed
US-10615348-B2 Organic light-emitting device SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-04-07 US disclosed
US-20190393424-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-12-26 US disclosed
US-20190157603-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-05-23 US disclosed
US-20170141323-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-05-18 US disclosed
US-20170141323-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11569452-B2 Organic light-emitting device CRY1, TRPA1, CRY2 RAC2 4601/4885RAC3 4630/4885CDC42 3203/4885
US-20190393424-A1 ORGANIC LIGHT-EMITTING DEVICE OR10J3, LIN28A, OR51E2 RAC2 3712/4885RAC3 3540/4885CDC42 1896/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.