SCHEMBL188741

SCHEMBL188741

O=c1[nH]c(=O)c2ncn([C@H]3O[C@@H](COP(=O)(O)O)C(O)C3O)c2[nH]1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IMPDH2 P12268 7/20 0.66
IMPDH1 P20839 2/20 0.66
TAS1R3 Q7RTX0 3/20 0.62
TAS1R1 Q7RTX1 3/20 0.62
DNPH1 O43598 3/20 0.58
FBP1 P09467 2/20 0.58
PRKAB2 O43741 1/20 0.58
TRPM2 O94759 1/20 0.58
LDHA P00338 1/20 0.58
ADRB2 P07550 1/20 0.58
SRC P12931 1/20 0.58
ADORA1 P30542 1/20 0.58
P2RY2 P41231 1/20 0.58
P2RY1 P47900 1/20 0.58
PRKAG1 P54619 1/20 0.58
PRKAA2 P54646 1/20 0.58
PDE4D Q08499 1/20 0.58
KCNH2 Q12809 1/20 0.58
PRKAA1 Q13131 1/20 0.58
PDE3A Q14432 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12727828 1.00 IMPDH2 (0.66) IMPDH2IMPDH1TAS1R3TAS1R1DNPH1
SCHEMBL22986473 1.00 IMPDH2 (0.66) IMPDH2IMPDH1TAS1R3TAS1R1DNPH1
SCHEMBL27862445 1.00 IMPDH2 (0.66) IMPDH2IMPDH1TAS1R3TAS1R1DNPH1
SCHEMBL4356337 1.00 IMPDH2 (0.66) IMPDH2IMPDH1TAS1R3TAS1R1DNPH1
SCHEMBL2217345 1.00 IMPDH2 (0.66) IMPDH2IMPDH1TAS1R3TAS1R1DNPH1
SCHEMBL188739 1.00 IMPDH2 (0.66) IMPDH2IMPDH1TAS1R3TAS1R1DNPH1
SCHEMBL20266268 0.99 IMPDH2 (0.65) IMPDH2IMPDH1TAS1R3TAS1R1DNPH1
SCHEMBL22635931 0.99 IMPDH2 (0.65) IMPDH2IMPDH1TAS1R3TAS1R1DNPH1
Phosphoric Acid SCHEMBL30728570 0.99 IMPDH2 (0.65) IMPDH2IMPDH1TAS1R3TAS1R1DNPH1
SCHEMBL28340155 0.99 IMPDH2 (0.65) IMPDH2IMPDH1TAS1R3TAS1R1DNPH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1175 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4223352-B1 DRUG-COATED BALLOON CATHETERS FOR BODY LUMENS UROTRONIC INC (US) 2026-05-27 EP claimed
US-20260114475-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME MARS, INCORPORATED (US) 2026-04-30 US claimed
US-12605342-B2 Polymer-encapsulated drug particles TONIC MEDICAL, INC. (US) 2026-04-21 US claimed
EP-4593631-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME Mars, Incorporated (US) 2025-08-06 EP claimed
US-12280226-B2 Drug-coated balloon catheters for body lumens UROTRONIC, INC. (US) 2025-04-22 US claimed
CN-119733157-A Drug coated balloon catheter for non-vascular stenosis 江苏长寿棒科技有限公司 2025-04-01 CN claimed
US-20250082582-A1 POLYMER-ENCAPSULATED DRUG PARTICLES TONIC MEDICAL, INC. 2025-03-13 US claimed
US-20250025673-A1 METHOD FOR TREATMENT OF AIRWAY STRICTURE OR STENOSIS AIRIVER MEDICAL, INC. 2025-01-23 US claimed
CN-119303213-A Drug-coated balloon catheter for body cavities 优敦力公司 2025-01-14 CN claimed
US-20240416013-A1 DRUG-COATED BALLOON CATHETERS FOR BODY LUMENS UROTRONIC, INC. 2024-12-19 US claimed
EP-1901622-A1 TASTE POTENTIATOR COMPOSITIONS AND BEVERAGES CONTAINING SAME Cadbury Adams USA LLC (US) 2008-03-26 EP claimed
CN-101132804-A Fetal skin cell protein compositions for the treatment of skin conditions, disorders or diseases and methods of making and using the same NEOCUTIS SA (CH) 2008-02-27 CN claimed
CN-100347562-C Magnetic resonance research method AIMOSJAM HEALTH AS (NO) 2007-11-07 CN claimed
US-20060286203-A1 Taste potentiator compositions and edible confectionery and chewing gum products containing same CADBURY ADAMS USA LLC 2006-12-21 US claimed
US-20060286259-A1 Taste potentiator compositions and beverages containing same CADBURY ADAMS USA LLC 2006-12-21 US claimed
US-20060286202-A1 Taste potentiator compositions and edible confectionery and chewing gum products containing same CADBURY ADAMS USA LLC 2006-12-21 US claimed
WO-2006127934-A2 TASTE POTENTIATOR COMPOSITIONS AND EDIBLE CONFECTIONERY AND CHEWING GUM PRODUCTS CONTAINING SAME CADBURY ADAMS USA, LLC (US) 2006-11-30 WO claimed
WO-2006127936-A2 TASTE POTENTIATOR COMPOSITIONS AND EDIBLE CONFECTIONERY AND CHEWING GUM PRODUCTS CONTAINING SAME CADBURY ADAMS USA LLC (US) 2006-11-30 WO claimed
WO-2006127935-A1 TASTE POTENTIATOR COMPOSITIONS AND BEVERAGES CONTAINING SAME CADBURY ADAMS USA LLC (US) 2006-11-30 WO claimed
US-5891452-A Cosmetic or dermatological composition containing at least one active principle precursor and a crosslinked poly(2-acrylamido-2-methylpropanesulphonic acid) polymer neutralized to at least 90% L'OREAL (FR) 1999-04-06 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12605342-B2 Polymer-encapsulated drug particles MUC1, SLC10A2, EGFR IMPDH2 4390/4885IMPDH1 4568/4885TAS1R3 374/4885
US-20250082582-A1 POLYMER-ENCAPSULATED DRUG PARTICLES CD47, GRPR, HSPA5 IMPDH2 4701/4885IMPDH1 4748/4885TAS1R3 1262/4885
US-20260114475-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME PIGS, TAS2R13, CEL IMPDH2 3474/4885IMPDH1 4172/4885TAS1R3 44/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.