Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9890035 | 0.82 | RXFP1 (0.46) | RXFP1KMT2AMEN1KDM4EIDO1 | |
| SCHEMBL21164304 | 0.79 | ALDH1A1 (0.43) | RXFP1KMT2AMEN1KDM4EIDO1 | |
| SCHEMBL29663621 | 0.75 | RXFP1 (0.55) | RXFP1KMT2AMEN1KDM4EIDO1 | |
| SCHEMBL9330701 | 0.74 | KMT2A (0.61) | RXFP1KMT2AKDM4ETSHRALDH1A1 | |
| SCHEMBL19221305 | 0.74 | RXFP1 (0.39) | RXFP1KMT2AMEN1KDM4EIDO1 | |
| SCHEMBL12292165 | 0.73 | RXFP1 (0.53) | RXFP1KMT2AMEN1KDM4EIDO1 | |
| SCHEMBL28033115 | 0.72 | RXFP1 (0.52) | RXFP1KMT2AMEN1KDM4EIDO1 | |
| SCHEMBL21180804 | 0.70 | KMT2A (0.42) | KMT2AMEN1TSHRALDH1A1LMNA | |
| SCHEMBL3336547 | 0.70 | PKM (0.57) | RXFP1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL222446 | 0.70 | RXFP1 (0.55) | RXFP1KMT2AMEN1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10358452-B2 | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydrocodone, prodrugs, methods of making and uses thereof | KEMPHARM, INC. (US) | 2019-07-23 | — | — | US | disclosed |
| US-20170143696-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF HYDROCODONE, PRODRUGS, METHODS OF MAKING AND USES THEREOF | ALTER DOMUS (US) LLC | 2017-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170143696-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF HYDROCODONE, PRODRUGS, METHODS OF MAKING AND USES THEREOF | CYP2B6, CYP3A43, CYP2D6 | RXFP1 1395/4885KMT2A 780/4885MEN1 4311/4885 |
| US-10358452-B2 | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydrocodone, prodrugs, methods of making and uses thereof | CYP2B6, CYP3A43, CYP2D6 | RXFP1 1395/4885KMT2A 780/4885MEN1 4311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.