Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12844701 | 0.88 | PGK1 (0.41) | PTGS2LMNAALDH1A1PDE1BACHE | |
| SCHEMBL7530707 | 0.81 | ALDH1A1 (0.51) | POLBL3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL16256378 | 0.78 | HPGD (0.41) | PTGS2POLBALDH1A1MAPTACHE | |
| SCHEMBL7525330 | 0.77 | ALDH1A1 (0.50) | L3MBTL1MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL19112726 | 0.77 | ACHE (0.39) | PTGS2POLBALDH1A1MAPTACHE | |
| SCHEMBL7529150 | 0.76 | KMT2A (0.55) | POLBL3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL5788061 | 0.74 | PDE4A (0.39) | L3MBTL1MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL12963092 | 0.74 | PTGS2 (0.50) | PTGS2MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL12403831 | 0.74 | ALDH1A1 (0.39) | PTGS2POLBALDH1A1MAPTACHE | |
| SCHEMBL8335123 | 0.74 | HTR2A (0.51) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9656956-B2 | Benzene, pyridine, and pyridazine derivatives | ESANEX, INC. (US) | 2017-05-23 | — | — | US | disclosed |