Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SLC34A1 | Q06495 | 2/20 | 0.32 |
| ▸ | NMT1 | P30419 | 1/20 | 0.32 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16502957 | 0.84 | PDE4D (0.39) | CASP3LMNAHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL18904098 | 0.75 | L3MBTL1 (0.44) | LMNAHTTSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL16502950 | 0.73 | LMNA (0.64) | LMNAHTTSMN1; SMN2L3MBTL1NMT1 | |
| SCHEMBL18904222 | 0.72 | NMT1 (0.68) | NMT1 | |
| SCHEMBL18904084 | 0.72 | MAPT (0.48) | LMNAHTTSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL18903943 | 0.72 | HRH3 (0.43) | LMNAHTTSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL21009247 | 0.71 | LOXL2 (0.45) | LMNAALDH1A1CYP2A6TSHR | |
| SCHEMBL18903780 | 0.71 | NMT1 (0.42) | LMNAHTTSMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL18903979 | 0.70 | SMN1; SMN2 (0.37) | LMNAHTTSMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL18904018 | 0.70 | NMT1 (0.65) | NMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2980076-B1 | Pyrazolyl derivatives | UNIV DUNDEE (GB) | 2017-05-31 | — | — | EP | disclosed |