Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14701232 | 0.88 | ALDH1A1 (0.38) | TSHRCA1CA2POLBHTT | |
| SCHEMBL13609719 | 0.84 | L3MBTL1 (0.46) | THRBCA1CA2POLBAPEX1 | |
| SCHEMBL13609812 | 0.83 | MEN1 (0.43) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL10035133 | 0.78 | TSHR (0.48) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL129437 | 0.78 | TSHR (0.62) | THRBTSHRCA1CA2POLB | |
| SCHEMBL10064079 | 0.77 | KDM4E (0.45) | THRBTSHRCA1CA2POLB | |
| SCHEMBL18904514 | 0.77 | MAPT (0.40) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL18906154 | 0.77 | KDM4E (0.40) | THRBTSHRCA1CA2POLB | |
| SCHEMBL19316665 | 0.77 | TSHR (0.45) | TSHRALDH1A1KDM4ELMNA | |
| SCHEMBL14701229 | 0.77 | POLB (0.39) | TSHRPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170153547-A1 | COATING COMPOSITIONS FOR USE WITH AN OVERCOATED PHOTORESIST | DUPONT SPECIALTY MATERIALS KOREA LTD (KR) | 2017-06-01 | — | — | US | disclosed |