SCHEMBL1890865

SCHEMBL1890865

NCCN(CCN)C(=O)CC(N)=O

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16133338 0.87 ALDH1A1 (0.30)
Hydrochloric Acid SCHEMBL10805157 0.85 LMNA (0.35)
SCHEMBL4529746 0.82 MAOA (0.44) MAOAMAOB
SCHEMBL3352929 0.78 ALDH1A1 (0.48)
SCHEMBL12081765 0.78 PAOX (0.34)
SCHEMBL16133337 0.76 ALDH1A1 (0.47)
SCHEMBL8928213 0.76 LMNA (0.39)
SCHEMBL8928215 0.75 LMNA (0.38)
SCHEMBL1203464 0.74 KDM4E (0.32)
SCHEMBL28676072 0.73 KDM4A (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117800868-A Low-viscosity self-thixotropic polyaspartic acid ester and preparation method and application thereof 深圳飞扬骏研新材料股份有限公司 2024-04-02 CN claimed
CN-117800868-B Low-viscosity self-thixotropic polyaspartic acid ester and preparation method and application thereof 深圳飞扬骏研新材料股份有限公司 2026-02-13 CN disclosed
CN-117800868-A Low-viscosity self-thixotropic polyaspartic acid ester and preparation method and application thereof 深圳飞扬骏研新材料股份有限公司 2024-04-02 CN disclosed
CN-117800868-A Low-viscosity self-thixotropic polyaspartic acid ester and preparation method and application thereof 深圳飞扬骏研新材料股份有限公司 2024-04-02 CN disclosed
US-7947839-B2 Heterocyclic-substituted bis-1,8 naphthalimide compounds, antibody drug conjugates, and methods of use GENENTECH, INC. (US) 2011-05-24 US disclosed
EP-1817059-A2 CONJUGATES OF 1,8-BIS-NAPHTHALIMIDES WITH AN ANTIBODY Genentech, Inc. (US) 2007-08-15 EP disclosed
WO-2007064345-A9 HETEROCYCLIC-SUBSTITUTED BIS-1,8 NAPHTHALIMIDE COMPOUNDS, ANTIBODY DRUG CONJUGATES, AND METHODS OF USE GENENTECH INC (US) 2007-07-12 WO disclosed
US-20070134243-A1 Antibody drug conjugates and methods GENENTECH, INC. 2007-06-14 US disclosed
US-20060182751-A1 Heterocyclic-substituted bis-1,8 naphthalimide compounds, antibody drug conjugates, and methods of use GENENTECH, INC. (US) 2006-08-17 US disclosed
WO-2006060533-A2 CONJUGATES OF 1, 8-BIS-NAPHTHALIMIDES WITH AN ANTIBODY GENENTECH, INC. (US) 2006-06-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060182751-A1 Heterocyclic-substituted bis-1,8 naphthalimide compounds, antibody drug conjugates, and methods of use CCNY, CCNI, MKI67 MAOA 1289/4885MAOB 1266/4885
US-20070134243-A1 Antibody drug conjugates and methods BOD1L1, MKI67, CCNI MAOA 1453/4885MAOB 952/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.