Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | IDO1 | P14902 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | DBH | P09172 | 1/20 | 0.33 |
| ▸ | TPMT | P51580 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | DEPTOR | Q8TB45 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13177269 | 0.82 | RAPGEF4 (0.33) | TSHRIDO1 | |
| SCHEMBL18873671 | 0.82 | HCAR1 (0.40) | TSHRIDO1CYP3A4ALDH1A1CHRM1 | |
| SCHEMBL14217865 | 0.77 | ENPP2 (0.38) | IDO1 | |
| SCHEMBL5442950 | 0.75 | ALDH1A1 (0.30) | ALDH1A1HSD17B10 | |
| SCHEMBL1047191 | 0.75 | TSHR (0.50) | TSHRIDO1CYP3A4TP53L3MBTL1 | |
| SCHEMBL2355446 | 0.73 | TSHR (0.57) | TSHRIDO1CYP3A4TP53L3MBTL1 | |
| SCHEMBL30123688 | 0.73 | — | — | |
| SCHEMBL6663215 | 0.73 | — | — | |
| SCHEMBL131126 | 0.71 | TSHR (0.53) | TSHRIDO1CYP3A4TP53L3MBTL1 | |
| SCHEMBL9687371 | 0.71 | TSHR (0.44) | TSHRIDO1CYP3A4TP53L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017091592-A1 | SUBSTITUTED BENZAMIDES USEFUL AS SODIUM CHANNEL BLOCKERS | GENENTECH, INC. (US) | 2017-06-01 | — | — | WO | disclosed |