Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPYD | Q12882 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HBB | P68871 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL887830 | 0.86 | DPYD (0.58) | DPYDGAAMAPTALDH1A1LMNA | |
| SCHEMBL1890981 | 0.83 | DPYD (0.50) | DPYDGAAMAPTALDH1A1LMNA | |
| SCHEMBL17553298 | 0.82 | DPYD (0.46) | DPYDGAAMAPTALDH1A1LMNA | |
| SCHEMBL1050748 | 0.80 | DPYD (0.47) | DPYDGAAMAPTALDH1A1LMNA | |
| SCHEMBL21295318 | 0.79 | DPYD (0.54) | DPYDGAAMAPTALDH1A1LMNA | |
| SCHEMBL31045516 | 0.79 | DPYD (0.54) | DPYDGAAMAPTALDH1A1LMNA | |
| SCHEMBL3485393 | 0.79 | DPYD (0.53) | DPYDGAAMAPTALDH1A1LMNA | |
| SCHEMBL2001029 | 0.79 | DPYD (0.53) | DPYDGAAMAPTALDH1A1LMNA | |
| SCHEMBL16585678 | 0.78 | GPR84 (0.46) | DPYDMAPTALDH1A1ATAD2TSHR | |
| SCHEMBL14177211 | 0.76 | DPYD (0.59) | DPYDGAAMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 209 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9932643-B2 | Detection of methicillin-resistant Staphylococcus aureus | ELITECHGROUP B.V. (NL) | 2018-04-03 | — | — | US | claimed |
| US-9677142-B2 | Detection of methicillin-resistant Staphylococcus aureus | ELITECHGROUP B.V. (NL) | 2017-06-13 | — | — | US | claimed |
| US-9328384-B2 | Droplet digital PCR with short minor groove probes | ELITECHGROUP B.V. (NL) | 2016-05-03 | — | — | US | claimed |
| US-20150275274-A1 | DETECTION OF METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS | ELITECH HOLDING B.V. | 2015-10-01 | — | — | US | claimed |
| EP-2714939-B1 | DETECTION OF METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS | ELITECH HOLDING BV (NL) | 2015-04-15 | — | — | EP | claimed |
| EP-1687609-B1 | FLUORESCENT PROBES FOR DNA DETECTION BY HYBRIDIZATION WITH IMPROVED SENSITIVITY AND LOW BACKGROUND | EPOCH BIOSCIENCES INC (US) | 2014-12-10 | — | — | EP | claimed |
| WO-2013048583-A2 | DETECTION OF METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS | ELITECH HOLDING B.V. (NL) | 2013-04-04 | — | — | WO | claimed |
| US-8067177-B2 | Amplification methods | EPOCH BIOSCIENCES, INC. (US) | 2011-11-29 | — | — | US | claimed |
| US-20110027780-A1 | AMPLIFICATION METHODS | ELITECHGROUP MDX LLC | 2011-02-03 | — | — | US | claimed |
| US-7790385-B2 | Abasic site endonuclease assay | ELITECH HOLDING B.V. (NL) | 2010-09-07 | — | — | US | claimed |
| US-7205105-B2 | Real-time linear detection probes: sensitive 5′-minor groove binder-containing probes for PCR analysis | EPOCH BIOSCIENCES, INC. (US) | 2007-04-17 | — | — | US | claimed |
| US-20070048758-A1 | IMPROVED PRIMER-BASED AMPLIFICATION METHODS | EPOCH BIOSCIENCES, INC. (US) | 2007-03-01 | — | — | US | claimed |
| WO-2006135765-A1 | IMPROVED PRIMER-BASED AMPLIFICATION METHODS | EPOCH BIOSCIENCES, INC. (US) | 2006-12-21 | — | — | WO | claimed |
| EP-1687609-A2 | FLUORESCENT PROBES FOR DNA DETECTION BY HYBRIDIZATION WITH IMPROVED SENSITIVITY AND LOW BACKGROUND | Epoch Biosciences, Inc. (US) | 2006-08-09 | — | — | EP | claimed |
| EP-1468112-A4 | REAL-TIME LINEAR DETECTION PROBES: SENSITIVE 5'-MINOR GROOVE BINDER-CONTAINING PROBES FOR PCR ANALYSIS | EPOCH BIOSCIENCES INC (US) | 2005-11-23 | — | — | EP | claimed |
| US-20050214797-A1 | Fluorescent probes for DNA detection by hybridization with improved sensitivity and low background | EPOCH BIOSCIENCES, INC (US) | 2005-09-29 | — | — | US | claimed |
| WO-2005043127-A2 | FLUORESCENT PROBES FOR DNA DETECTION BY HYBRIDIZATION WITH IMPROVED SENSITIVITY AND LOW BACKGROUND | EPOCH BIOSCIENCES, INC. (US) | 2005-05-12 | — | — | WO | claimed |
| EP-1468112-A2 | REAL-TIME LINEAR DETECTION PROBES: SENSITIVE 5'-MINOR GROOVE BINDER-CONTAINING PROBES FOR PCR ANALYSIS | Epoch Biosciences, Inc. (US) | 2004-10-20 | — | — | EP | claimed |
| US-20030175728-A1 | Real-time linear detection probes: sensitive 5'-minor groove binder-containing probes for PCR analysis | EPOCH BIOSCIENCES, INC. (US) | 2003-09-18 | — | — | US | claimed |
| WO-2003062445-A2 | REAL-TIME LINEAR DETECTION PROBES: SENSITIVE 5'-MINOR GROOVE BINDER-CONTAINING PROBES FOR PCR ANALYSIS | EPOCH BIOSCIENCES, INC. (US) | 2003-07-31 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030175728-A1 | Real-time linear detection probes: sensitive 5'-minor groove binder-containing probes for PCR analysis | RNGTT, DCLRE1B, CNBP | DPYD 598/4885GAA 326/4885MAPT 4658/4885 |
| US-20050214797-A1 | Fluorescent probes for DNA detection by hybridization with improved sensitivity and low background | SSBP1, DDB1, DNA2 | DPYD 378/4885GAA 2125/4885MAPT 3770/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.