Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.46 |
| ▸ | DPYD | Q12882 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.36 |
| ▸ | TYMP | P19971 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31045506 | 0.98 | DPYD (0.46) | GPR84DPYDKCNH2ATAD2CYP3A4 | |
| SCHEMBL1050748 | 0.94 | DPYD (0.47) | GPR84DPYDATAD2CYP3A4TSHR | |
| SCHEMBL16586691 | 0.92 | GPR84 (0.43) | GPR84DPYDKCNH2CYP3A4TSHR | |
| SCHEMBL16586721 | 0.92 | GPR84 (0.43) | GPR84DPYDKCNH2CYP3A4TSHR | |
| SCHEMBL1890981 | 0.87 | DPYD (0.50) | DPYDATAD2TSHRKDM4EALDH1A1 | |
| SCHEMBL1586447 | 0.81 | DPYD (0.40) | GPR84DPYDCYP3A4TSHRCYP2C9 | |
| SCHEMBL3485393 | 0.80 | DPYD (0.53) | DPYDATAD2TSHRALDH1A1MAPT | |
| SCHEMBL31045516 | 0.80 | DPYD (0.54) | DPYDATAD2TSHRALDH1A1MAPT | |
| SCHEMBL22748451 | 0.70 | FFAR1 (0.42) | GPR84KCNH2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6573665 | 0.69 | TYMP (0.51) | GPR84ATAD2TYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10285939-B2 | Means and methods for ocular drug delivery | EBERHARD KARLS UNIVERSITÄT TÜBINGEN MEDIZINISCHE FAKULTÄT (DE) | 2019-05-14 | — | — | US | disclosed |
| EP-3057572-B1 | MEANS AND METHODS FOR OCULAR DRUG DELIVERY | EBERHARD KARLS UNIVERSITÄT TÜBINGEN MEDIZINISCHE FAKULTÄT (DE) | 2018-01-31 | — | — | EP | disclosed |
| US-20160346203-A1 | MEANS AND METHODS FOR OCULAR DRUG DELIVERY | EBERHARD KARLS UNIVERSITÄT TÜBINGEN MEDIZINISCHE FAKULTÄT (DE) | 2016-12-01 | — | — | US | disclosed |
| EP-3057572-A1 | MEANS AND METHODS FOR OCULAR DRUG DELIVERY | Rijksuniversiteit Groningen (NL) | 2016-08-24 | — | — | EP | disclosed |
| WO-2015041520-A1 | MEANS AND METHODS FOR OCULAR DRUG DELIVERY | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2015-03-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10285939-B2 | Means and methods for ocular drug delivery | UACA, PDE6C, CRYAA | GPR84 1696/4885DPYD 3498/4885KCNH2 4115/4885 |
| US-20160346203-A1 | MEANS AND METHODS FOR OCULAR DRUG DELIVERY | UACA, PDE6C, CRYAA | GPR84 1696/4885DPYD 3498/4885KCNH2 4115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.