Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPYD | Q12882 | 4/20 | 0.44 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.36 |
| ▸ | HMGCR | P04035 | 2/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.31 |
| ▸ | TYMP | P19971 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1050748 | 0.89 | DPYD (0.47) | DPYDATAD2GPR84GAAALDH1A1 | |
| SCHEMBL31045506 | 0.85 | DPYD (0.46) | DPYDATAD2GPR84GAAALDH1A1 | |
| SCHEMBL16585678 | 0.84 | GPR84 (0.46) | DPYDATAD2GPR84ALDH1A1MAPT | |
| SCHEMBL1890981 | 0.80 | DPYD (0.50) | DPYDATAD2GAAALDH1A1LMNA | |
| SCHEMBL16586721 | 0.77 | GPR84 (0.43) | DPYDGPR84LMNAMAPTTSHR | |
| SCHEMBL16586691 | 0.77 | GPR84 (0.43) | DPYDGPR84LMNAMAPTTSHR | |
| SCHEMBL1586445 | 0.77 | DPYD (0.40) | DPYDGPR84ALDH1A1LMNAMAPT | |
| SCHEMBL21295318 | 0.73 | DPYD (0.54) | DPYDATAD2GAAALDH1A1LMNA | |
| SCHEMBL31045516 | 0.73 | DPYD (0.54) | DPYDATAD2GAAALDH1A1LMNA | |
| SCHEMBL887754 | 0.70 | DPYD (0.50) | DPYDATAD2GAAALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4737574-A2 | POLY-TAILED AND POLY-CAPPED MRNA AND USES THEREOF | The Broad Institute Inc. (US) | 2026-05-06 | — | — | EP | disclosed |
| CN-119095964-A | Multi-tail and multi-cap mRNA and uses thereof | 博德研究所 | 2024-12-06 | — | — | CN | disclosed |
| US-20240392311-A1 | POLY-TAILED AND POLY-CAPPED MRNA AND USES THEREOF | THE BROAD INSTITUTE, INC. (US) | 2024-11-28 | — | — | US | disclosed |
| EP-4466074-A1 | POLY-TAILED AND POLY-CAPPED MRNA AND USES THEREOF | The Broad Institute Inc. (US) | 2024-11-27 | — | — | EP | disclosed |
| WO-2024211297-A2 | PROTEIN / POLYPEPTIDE SEQUENCING BY EXPANSION (PROSE) | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2024-10-10 | — | — | WO | disclosed |
| WO-2023141474-A9 | POLY-TAILED AND POLY-CAPPED MRNA AND USES THEREOF | THE BROAD INSTITUTE, INC. (US) | 2023-10-26 | — | — | WO | disclosed |
| WO-2023141474-A1 | POLY-TAILED AND POLY-CAPPED MRNA AND USES THEREOF | THE BROAD INSTITUTE, INC. (US) | 2023-07-27 | — | — | WO | disclosed |