SCHEMBL1892089

SCHEMBL1892089

CCCC(=O)C1C(C)=CCCC1(C)C

nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.48
CYP3A4 P08684 1/20 0.48
ALOX15 P16050 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
HSD17B10 Q99714 1/20 0.34
GAA P10253 2/20 0.34
KDM4E B2RXH2 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9837159 0.91 ALDH1A1 (0.46) ALDH1A1CYP3A4ALOX15TDP1GAA
SCHEMBL17129799 0.87 ALDH1A1 (0.54) ALDH1A1CYP3A4ALOX15TDP1GAA
SCHEMBL11230598 0.84 ALDH1A1 (0.46) ALDH1A1CYP3A4ALOX15TDP1GAA
SCHEMBL7700786 0.80 TSHR (0.41) ALDH1A1CYP3A4ALOX15TDP1HSD17B10
SCHEMBL18308881 0.79 ALDH1A1 (0.43) ALDH1A1CYP3A4ALOX15TDP1GAA
SCHEMBL11451383 0.78 ALDH1A1 (0.43) ALDH1A1CYP3A4ALOX15TDP1GAA
SCHEMBL9837141 0.78 ALDH1A1 (0.46) ALDH1A1CYP3A4ALOX15TDP1GAA
SCHEMBL1891917 0.78 ALDH1A1 (0.43) ALDH1A1CYP3A4ALOX15TDP1GAA
SCHEMBL4593867 0.78 ALOX15 (0.46) ALDH1A1CYP3A4ALOX15TDP1GAA
SCHEMBL1784164 0.78 ALDH1A1 (0.46) ALDH1A1CYP3A4ALOX15TDP1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7935669-B2 Compounds for a controlled release of active molecules FIRMENICH SA (CH) 2011-05-03 US disclosed
US-7723286-B2 Compounds for a controlled release of active molecules FIRMENICH SA (CH) 2010-05-25 US disclosed
US-20090181878-A1 COMPOUNDS FOR A CONTROLLED RELEASE OF ACTIVE MOLECULES FIRMENICH SA 2009-07-16 US disclosed
EP-1460994-B1 COMPOUNDS FOR A CONTROLLED RELEASE OF ACTIVE MOLECULES FIRMENICH & CIE (CH) 2008-10-01 EP disclosed
US-20040220074-A1 Compounds for a controlled release of active molecules FIRMENICH SA (CH) 2004-11-04 US disclosed
EP-0012436-B1 PROCESS FOR HYDROGENATION OF 2,6,6-TRIMETHYL CYCLOHEXENE DERIVATIVES, PRODUCTS PRODUCED THEREBY AND ORGANOLEPTIC USES OF SAID PRODUCTS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1982-11-24 EP disclosed
US-4360032-A Use of hydrogenated derivatives of 2,6,6-trimethyl-cyclohexene derivatives in augmenting or enhancing the aroma or taste of smoking tobacco and smoking tobacco articles INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1982-11-23 US disclosed
US-4324704-A PERFUMES CONTAINING HYDROGENATION PRODUCTS OF DAMASCENONE INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1982-04-13 US disclosed
US-4315953-A Process for augmenting or enhancing the aroma or taste of raspberry flavored foodstuffs using 2,6,6-trimethylcyclohexene derivatives INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1982-02-16 US disclosed
US-4313842-A FOR DETERGENTS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1982-02-02 US disclosed
US-4311754-A FOR FABRIC SOFTENERS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1982-01-19 US disclosed
US-4292447-A Process for hydrogenation of 2,6,6-trimethyl cyclohexene derivatives, products produced thereby and organoleptic uses of said products INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1981-09-29 US disclosed
EP-0012436-A1 Process for hydrogenation of 2,6,6-trimethyl cyclohexene derivatives, products produced thereby and organoleptic uses of said products INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1980-06-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040220074-A1 Compounds for a controlled release of active molecules ACLY, PTGES, NOTUM ALDH1A1 355/4885CYP3A4 199/4885ALOX15 58/4885
US-20090181878-A1 COMPOUNDS FOR A CONTROLLED RELEASE OF ACTIVE MOLECULES ACLY, PTGES, PPOX ALDH1A1 315/4885CYP3A4 208/4885ALOX15 103/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.