Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 3/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4889770 | 0.89 | HCAR2 (0.47) | LMNANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28444213 | 0.81 | LMNA (0.56) | LMNANPC1RECQLRAB9ASMN1; SMN2 | |
| SCHEMBL7263670 | 0.81 | LMNA (0.68) | LMNANPC1RECQLRAB9ASMN1; SMN2 | |
| SCHEMBL4580407 | 0.80 | TSHR (0.63) | NAAAALDH1A1TSHRTDP1 | |
| SCHEMBL146245 | 0.80 | POLB (0.55) | LMNANPC1RECQLRAB9ASMN1; SMN2 | |
| SCHEMBL1603035 | 0.80 | ALDH1A1 (0.50) | LMNASMN1; SMN2ALDH1A1TSHRTDP1 | |
| SCHEMBL232155 | 0.79 | POLB (0.57) | LMNANPC1RECQLRAB9ASMN1; SMN2 | |
| SCHEMBL233287 | 0.79 | POLB (0.57) | LMNANPC1RECQLRAB9ASMN1; SMN2 | |
| SCHEMBL1562514 | 0.79 | POLB (0.57) | LMNANPC1RECQLRAB9ASMN1; SMN2 | |
| SCHEMBL342384 | 0.79 | POLB (0.57) | LMNANPC1RECQLRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670145-B2 | Process for preparing 1,1-disubstituted ethylene monomers | AFINITICA TECHNOLOGIES, S. L. (ES) | 2017-06-06 | — | — | US | disclosed |