Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CECR2 | Q9BXF3 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 3/20 | 0.43 |
| ▸ | TAF1 | P21675 | 2/20 | 0.43 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.38 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.38 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.38 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.38 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.38 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 2/20 | 0.37 |
| ▸ | TPX2 | Q9ULW0 | 2/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18924424 | 0.84 | MAPK14 (0.41) | CECR2MAPTBRD4TAF1BRD9 | |
| SCHEMBL22221034 | 0.71 | LMNA (0.43) | MAPTCYP2D6CLK4CYP1A2CYP3A4 | |
| SCHEMBL22220936 | 0.69 | PTGS2 (0.56) | MAPTCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL22259673 | 0.68 | BRD9 (0.42) | CECR2MAPTBRD4TAF1TRIM24 | |
| SCHEMBL4790487 | 0.68 | IKBKB (0.69) | PRKCQCLK4PIK3R1PIK3CAMTOR | |
| SCHEMBL19391415 | 0.68 | HSD17B1 (0.34) | CECR2MAPTBRD4AURKATPX2 | |
| SCHEMBL17748906 | 0.68 | CECR2 (1.00) | CECR2BRD4TAF1TRIM24SMARCA2 | |
| SCHEMBL18924375 | 0.67 | NSD2 (0.51) | ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL22259806 | 0.67 | PRKAB2 (0.46) | CECR2MAPT | |
| SCHEMBL18924423 | 0.66 | MAPK14 (0.45) | CECR2MAPTBRD4TAF1BRD9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670142-B2 | 1,3-diaminocyclopentane carboxamide derivatives | MERCK PATENT GMBH (DE) | 2017-06-06 | — | — | US | disclosed |