Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.43 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.42 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | SPR | P35270 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | AGER | Q15109 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31645626 | 0.83 | ALDH1A1 (0.42) | L3MBTL1KDM4EALDH1A1CYP3A4MAPT | |
| SCHEMBL108876 | 0.78 | L3MBTL1 (0.62) | TLR7EGLN2FTOL3MBTL1KDM4E | |
| SCHEMBL28048185 | 0.78 | TLR7 (0.48) | TLR7EGLN2FTOL3MBTL1KDM4E | |
| SCHEMBL2304193 | 0.76 | LMNA (0.35) | TLR7L3MBTL1KDM4EALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL6569637 | 0.76 | L3MBTL1 (0.60) | TLR7EGLN2FTOL3MBTL1KDM4E | |
| SCHEMBL31646056 | 0.76 | FEN1 (0.50) | L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL27832422 | 0.75 | EGLN2 (0.49) | TLR7EGLN2FTOL3MBTL1KDM4E | |
| SCHEMBL7833009 | 0.75 | L3MBTL1 (0.51) | TLR7EGLN2FTOL3MBTL1KDM4E | |
| SCHEMBL31645520 | 0.74 | GRM5 (0.43) | KDM4EALDH1A1CYP3A4MAPTALOX15 | |
| SCHEMBL1829785 | 0.74 | KDM4E (0.47) | TLR7EGLN2FTOL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025137640-A1 | AZASPIRO WRN INHIBITORS | GILEAD SCIENCES, INC. (US) | 2025-06-26 | — | — | WO | disclosed |
| EP-4347596-A1 | TRIAZOLO-PYRIMIDINE ANALOGUES FOR TREATING DISEASES CONNECTED TO THE INHIBITON OF WERNER SYNDROME RECQ HELICASE (WRN) | Novartis AG (CH) | 2024-04-10 | — | — | EP | disclosed |
| US-20230046859-A1 | Bicyclic Compounds and their Uses | NOVARTIS PHARMA AG (CH) | 2023-02-16 | — | — | US | disclosed |
| WO-2022249060-A1 | TRIAZOLO-PYRIMIDINE ANALOGUES FOR TREATING DISEASES CONNECTED TO THE INHIBITON OF WERNER SYNDROME RECQ HELICASE (WRN) | NOVARTIS AG (CH) | 2022-12-01 | — | — | WO | disclosed |
| EP-2718298-A1 | SUBSTITUTED PYRIDINES HAVING HERBICIDAL ACTIVITY | BASF SE (DE) | 2014-04-16 | — | — | EP | disclosed |
| US-8338337-B2 | Substituted pyridines having a herbicidal effect | BASF SE (DE) | 2012-12-25 | — | — | US | disclosed |
| WO-2012168397-A1 | SUBSTITUTED PYRIDINES HAVING HERBICIDAL ACTIVITY | BASF SE (DE) | 2012-12-13 | — | — | WO | disclosed |
| WO-2012168397-A1 | SUBSTITUTED PYRIDINES HAVING HERBICIDAL ACTIVITY | BASF SE (DE) | 2012-12-13 | — | — | WO | disclosed |
| US-20110224078-A1 | Substituted Pyridines Having a Herbicidal Effect | BASF SE (DE) | 2011-09-15 | — | — | US | disclosed |
| US-20110201501-A1 | Substituted Pyridines Having a Herbicidal Effect | BASF SE (DE) | 2011-08-18 | — | — | US | disclosed |
| WO-2011057942-A1 | INSECTICIDAL METHODS USING PYRIDINE COMPOUNDS | BASF SE (DE) | 2011-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110201501-A1 | Substituted Pyridines Having a Herbicidal Effect | DDT, PNPO, HPD | TLR7 3745/4885EGLN2 570/4885FTO 424/4885 |
| US-20230046859-A1 | Bicyclic Compounds and their Uses | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, C1R, F12 | TLR7 196/4885EGLN2 2974/4885FTO 3943/4885 |
| US-20110224078-A1 | Substituted Pyridines Having a Herbicidal Effect | DDT, PNPO, HPD | TLR7 3745/4885EGLN2 570/4885FTO 424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.