Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LOX | P28300 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18946198 | 0.80 | RAB9A (0.47) | LMNASMN1; SMN2ALDH1A1KDM4EKMT2A | |
| SCHEMBL710011 | 0.79 | LOX (0.46) | LOX | |
| SCHEMBL5645669 | 0.78 | CA2 (0.61) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL22558460 | 0.78 | LMNA (0.43) | LMNASMN1; SMN2ALDH1A1HTTKDM4E | |
| SCHEMBL1306384 | 0.76 | GABRA1 (0.38) | LMNASMN1; SMN2ALDH1A1KDM4EKMT2A | |
| SCHEMBL5805726 | 0.75 | LMNA (0.55) | LMNASMN1; SMN2ALDH1A1HTTKDM4E | |
| SCHEMBL1306505 | 0.73 | APP (0.41) | LMNASMN1; SMN2ALDH1A1KDM4EKMT2A | |
| SCHEMBL2224520 | 0.73 | TSHR (0.60) | LMNASMN1; SMN2ALDH1A1HTTKDM4E | |
| SCHEMBL18946200 | 0.73 | CA12 (0.55) | LMNASMN1; SMN2ALDH1A1HTTKDM4E | |
| Trimethylammonium SCHEMBL28031212 | 0.73 | GABRA1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017093544-A1 | ALKYNYL PHOSPHINE GOLD COMPLEXES FOR TREATING BACTERIAL INFECTIONS | AUSPHERIX LIMITED (GB) | 2017-06-08 | — | — | WO | disclosed |