Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL190288 | 0.90 | PARP10 (0.56) | SMN1; SMN2NPC1RAB9AMAPTL3MBTL1 | |
| SCHEMBL27843421 | 0.89 | SMN1; SMN2 (0.49) | SMN1; SMN2HTTLMNANPC1RAB9A | |
| SCHEMBL190018 | 0.88 | MAPT (0.50) | SMN1; SMN2NPC1RAB9AMAPTL3MBTL1 | |
| SCHEMBL188962 | 0.88 | RAB9A (0.57) | SMN1; SMN2LMNANPC1RAB9AMAPT | |
| SCHEMBL189828 | 0.86 | L3MBTL1 (0.61) | SMN1; SMN2HTTLMNANPC1RAB9A | |
| SCHEMBL189490 | 0.86 | RAB9A (0.60) | SMN1; SMN2NPC1RAB9AMAPTL3MBTL1 | |
| SCHEMBL189525 | 0.86 | RAB9A (0.60) | SMN1; SMN2NPC1RAB9AMAPTL3MBTL1 | |
| SCHEMBL189840 | 0.86 | RAB9A (0.59) | SMN1; SMN2NPC1RAB9AMAPTL3MBTL1 | |
| SCHEMBL189148 | 0.85 | L3MBTL1 (0.49) | SMN1; SMN2NPC1RAB9AMAPTL3MBTL1 | |
| SCHEMBL189327 | 0.85 | NR4A2 (0.48) | SMN1; SMN2NPC1RAB9AMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9290464-B2 | Pharmaceutical composition for inhibiting apoptosis of neuron or neurodegeneration | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2016-03-22 | — | — | US | claimed |
| EP-2401263-B1 | SUBSTITUTED AZOLE DERIVATIVES, PHARMACEUTICAL COMPOSITION CONTAINING THE DERIVATIVES, AND METHOD FOR TREATING PARKINSON'S DISEASE USING THE SAME | SK BIOPHARMACEUTICALS CO LTD (KR) | 2016-02-17 | — | — | EP | claimed |
| US-20140350062-A1 | PHARMACEUTICAL COMPOSITION FOR INHIBITING APOPTOSIS OF NEURON OR NEURODEGENERATION | SK BIOPHARMACEUTICALS CO LTD (KR) | 2014-11-27 | — | — | US | claimed |
| US-8841335-B2 | Pharmaceutical composition for inhibiting apoptosis of neuron or neurodegeneration | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2014-09-23 | — | — | US | claimed |
| US-8828992-B2 | Substituted azole derivatives, pharmaceutical composition containing the derivatives, and method for treating Parkinson's disease using the same | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2014-09-09 | — | — | US | claimed |
| EP-2566475-A2 | PHARMACEUTICAL COMPOSITION FOR INHIBITING APOPTOSIS OF NEURON OR NEURODEGENERATION | SK Biopharmaceuticals Co., Ltd. (KR) | 2013-03-13 | — | — | EP | claimed |
| US-20130046001-A1 | PHARMACEUTICAL COMPOSITION FOR INHIBITING APOPTOSIS OF NEURON OR NEURODEGENERATION | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2013-02-21 | — | — | US | claimed |
| EP-2401263-A2 | SUBSTITUTED AZOLE DERIVATIVES, PHARMACEUTICAL COMPOSITION CONTAINING THE DERIVATIVES, AND METHOD FOR TREATING PARKINSON'S DISEASE USING THE SAME | SK Biopharmaceuticals Co., Ltd. (KR) | 2012-01-04 | — | — | EP | claimed |
| US-20110301150-A1 | SUBSTITUTED AZOLE DERIVATIVES, PHARMACEUTICAL COMPOSITION CONTAINING THE DERIVATIVES, AND METHOD FOR TREATING PARKINSON'S DISEASE USING THE SAME | SK BIOPHARMACEUTICALS CO., LTD. | 2011-12-08 | — | — | US | claimed |
| WO-2011139079-A2 | PHARMACEUTICAL COMPOSITION FOR INHIBITING APOPTOSIS OF NEURON OR NEURODEGENERATION | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2011-11-10 | — | — | WO | claimed |
| WO-2010098600-A2 | SUBSTITUTED AZOLE DERIVATIVES, PHARMACEUTICAL COMPOSITION CONTAINING THE DERIVATIVES, AND METHOD FOR TREATING PARKINSON'S DISEASE USING THE SAME | SK HOLDINGS CO., LTD. (KR) | 2010-09-02 | — | — | WO | claimed |
| US-9290464-B2 | Pharmaceutical composition for inhibiting apoptosis of neuron or neurodegeneration | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2016-03-22 | — | — | US | disclosed |
| EP-2401263-B1 | SUBSTITUTED AZOLE DERIVATIVES, PHARMACEUTICAL COMPOSITION CONTAINING THE DERIVATIVES, AND METHOD FOR TREATING PARKINSON'S DISEASE USING THE SAME | SK BIOPHARMACEUTICALS CO LTD (KR) | 2016-02-17 | — | — | EP | disclosed |
| US-20140350062-A1 | PHARMACEUTICAL COMPOSITION FOR INHIBITING APOPTOSIS OF NEURON OR NEURODEGENERATION | SK BIOPHARMACEUTICALS CO LTD (KR) | 2014-11-27 | — | — | US | disclosed |
| US-8841335-B2 | Pharmaceutical composition for inhibiting apoptosis of neuron or neurodegeneration | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2014-09-23 | — | — | US | disclosed |
| CN-102333764-A | Substituted azole derivatives, pharmaceutical composition containing the derivatives, and method for treating parkinson's disease using the same | SK HOLDINGS CO LTD | 2012-01-25 | — | — | CN | disclosed |
| EP-2401263-A2 | SUBSTITUTED AZOLE DERIVATIVES, PHARMACEUTICAL COMPOSITION CONTAINING THE DERIVATIVES, AND METHOD FOR TREATING PARKINSON'S DISEASE USING THE SAME | SK Biopharmaceuticals Co., Ltd. (KR) | 2012-01-04 | — | — | EP | disclosed |
| US-20110301150-A1 | SUBSTITUTED AZOLE DERIVATIVES, PHARMACEUTICAL COMPOSITION CONTAINING THE DERIVATIVES, AND METHOD FOR TREATING PARKINSON'S DISEASE USING THE SAME | SK BIOPHARMACEUTICALS CO., LTD. | 2011-12-08 | — | — | US | disclosed |
| WO-2011139079-A2 | PHARMACEUTICAL COMPOSITION FOR INHIBITING APOPTOSIS OF NEURON OR NEURODEGENERATION | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2011-11-10 | — | — | WO | disclosed |
| WO-2010098600-A2 | SUBSTITUTED AZOLE DERIVATIVES, PHARMACEUTICAL COMPOSITION CONTAINING THE DERIVATIVES, AND METHOD FOR TREATING PARKINSON'S DISEASE USING THE SAME | SK HOLDINGS CO., LTD. (KR) | 2010-09-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110301150-A1 | SUBSTITUTED AZOLE DERIVATIVES, PHARMACEUTICAL COMPOSITION CONTAINING THE DERIVATIVES, AND METHOD FOR TREATING PARKINSON'S DISEASE USING THE SAME | MAOB, MAOA, PARK7 | SMN1; SMN2 268/4885HTT 130/4885LMNA 2711/4885 |
| US-20140350062-A1 | PHARMACEUTICAL COMPOSITION FOR INHIBITING APOPTOSIS OF NEURON OR NEURODEGENERATION | BAX, NLN, CASP3 | SMN1; SMN2 15/4885HTT 41/4885LMNA 386/4885 |
| US-20130046001-A1 | PHARMACEUTICAL COMPOSITION FOR INHIBITING APOPTOSIS OF NEURON OR NEURODEGENERATION | BAX, NLN, CASP3 | SMN1; SMN2 15/4885HTT 41/4885LMNA 386/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.