Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARK7 | Q99497 | 1/20 | 0.49 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.47 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.47 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.45 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.45 |
| ▸ | TGM2 | P21980 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | CASP4 | P49662 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18954858 | 0.84 | ACHE (0.63) | PARK7ACHEALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL18954751 | 0.81 | ALDH1A1 (0.67) | PARK7ACHEALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL18955172 | 0.81 | CTRC (0.54) | PARK7ACHEALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL18954793 | 0.81 | ALDH3A1 (0.69) | PARK7ALDH1A1ALDH2ALDH3A1CHRM5 | |
| SCHEMBL18954774 | 0.81 | CHRM5 (0.66) | PARK7ALDH1A1ALDH2ALDH3A1CHRM5 | |
| SCHEMBL18954626 | 0.81 | PARK7 (0.49) | PARK7ACHEALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL18955277 | 0.81 | PARK7 (0.63) | PARK7ALDH1A1ALDH3A1TP53MAPT | |
| SCHEMBL18974327 | 0.81 | CES1 (0.62) | PARK7ACHEALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL18954540 | 0.79 | PARK7 (0.49) | PARK7ACHEALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL18954527 | 0.78 | CASP1 (0.70) | PARK7ACHEALDH1A1ALDH2ALDH3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017099695-A1 | N-[(AMINOSULFONYL)PHENYL]-2-(1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDENE)-HYDRAZINECARBOTHIOAMIDE DERIVATIVES FOR TREATING CANCER AND IMMUNOLOGICAL DISORDERS | ISTANBUL UNIVERSITESI REKTORLUGU (TR) | 2017-06-15 | — | — | WO | disclosed |