SCHEMBL189596

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL189490	0.89	RAB9A (0.60)	RAB9ANPC1MAOBL3MBTL1MAPT
	SCHEMBL189566	0.87	RAB9A (0.54)	RAB9ANPC1MAOBL3MBTL1MAPT
	SCHEMBL189828	0.87	L3MBTL1 (0.61)	RAB9ANPC1L3MBTL1MAPTSMN1; SMN2
	SCHEMBL253621	0.86	MAOB (0.55)	RAB9ANPC1MAOAMAOBL3MBTL1
	SCHEMBL189410	0.85	RAB9A (0.51)	RAB9ANPC1L3MBTL1MAPTSMN1; SMN2
	SCHEMBL189525	0.85	RAB9A (0.60)	RAB9ANPC1L3MBTL1MAPTSMN1; SMN2
	SCHEMBL190288	0.85	PARP10 (0.56)	RAB9ANPC1MAOBL3MBTL1MAPT
	SCHEMBL190018	0.85	MAPT (0.50)	RAB9ANPC1MAOBL3MBTL1MAPT
	SCHEMBL15774353	0.84	MAOB (0.52)	RAB9ANPC1MAOAMAOBL3MBTL1
	SCHEMBL189840	0.84	RAB9A (0.59)	RAB9ANPC1L3MBTL1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.