Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 19/20 | 0.43 |
| ▸ | FPR1 | P21462 | 15/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30133743 | 1.00 | FPR2 (0.43) | FPR2FPR1F2F10PRSS1 | |
| SCHEMBL18964488 | 1.00 | FPR2 (0.43) | FPR2FPR1F2F10PRSS1 | |
| SCHEMBL30133740 | 1.00 | FPR2 (0.43) | FPR2FPR1F2F10PRSS1 | |
| SCHEMBL28377662 | 1.00 | FPR2 (0.43) | FPR2FPR1F2F10PRSS1 | |
| SCHEMBL18964489 | 0.88 | DGAT1 (0.46) | FPR2FPR1F2F10PRSS1 | |
| SCHEMBL22179924 | 0.88 | FPR2 (0.45) | FPR2FPR1 | |
| SCHEMBL18291719 | 0.88 | FPR2 (0.43) | FPR2FPR1F2F10PRSS1 | |
| SCHEMBL29462396 | 0.88 | FPR2 (0.43) | FPR2FPR1F2F10PRSS1 | |
| SCHEMBL18291706 | 0.85 | FPR2 (0.42) | FPR2FPR1F2F10PRSS1 | |
| SCHEMBL18955177 | 0.83 | FPR2 (0.45) | FPR2FPR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110996950-B | Piperidinone formyl peptide 2 receptor agonists and formyl peptide 1 receptor agonists | 百时美施贵宝公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-108368046-B | Piperidinone formyl peptide 2 receptor and formyl peptide 1 receptor agonists | 百时美施贵宝公司 | 2022-01-14 | — | — | CN | disclosed |
| US-11186544-B2 | Piperidinone formyl peptide 2 receptor and formyl peptide 1 receptor agonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-11-30 | — | — | US | disclosed |
| EP-3414227-B1 | PIPERIDINONE FORMYL PEPTIDE 2 RECEPTOR AND FORMYL PEPTIDE 1 RECEPTOR AGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2021-11-24 | — | — | EP | disclosed |
| US-10717708-B2 | Piperidinone formyl peptide 2 receptor and formyl peptide 1 receptor agonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-07-21 | — | — | US | disclosed |
| US-10717708-B2 | Piperidinone formyl peptide 2 receptor and formyl peptide 1 receptor agonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-07-21 | — | — | US | disclosed |
| CN-110996950-A | Piperidinone formyl peptide 2 receptor agonists and formyl peptide 1 receptor agonists | 百时美施贵宝公司 | 2020-04-10 | — | — | CN | disclosed |
| US-20180327358-A1 | PIPERIDINONE FORMYL PEPTIDE 2 RECEPTOR AND FORMYL PEPTIDE 1 RECEPTOR AGONISTS | SYNGENE INTERNATIONAL LIMITED (IN) | 2018-11-15 | — | — | US | disclosed |
| WO-2017100390-A1 | PIPERIDINONE FORMYL PEPTIDE 2 RECEPTOR AND FORMYL PEPTIDE 1 RECEPTOR AGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-06-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10717708-B2 | Piperidinone formyl peptide 2 receptor and formyl peptide 1 receptor agonists | FPR1, FPR2, FPR3 | FPR2 2/4885FPR1 1/4885F2 358/4885 |
| US-11186544-B2 | Piperidinone formyl peptide 2 receptor and formyl peptide 1 receptor agonists | FPR1, FPR2, FPR3 | FPR2 2/4885FPR1 1/4885F2 309/4885 |
| US-20180327358-A1 | PIPERIDINONE FORMYL PEPTIDE 2 RECEPTOR AND FORMYL PEPTIDE 1 RECEPTOR AGONISTS | FPR1, FPR2, FPR3 | FPR2 2/4885FPR1 1/4885F2 358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.