SCHEMBL30133743

SCHEMBL30133743

CC(C)(C)OC(=O)N[C@H]1CCCN(c2ccc(I)nc2)C1=O

nearest known ligand 0.43

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 19/20 0.43
FPR1 P21462 15/20 0.43
F2 P00734 1/20 0.39
F10 P00742 1/20 0.39
PRSS1 P07477 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18964487 1.00 FPR2 (0.43) FPR2FPR1F2F10PRSS1
SCHEMBL18964488 1.00 FPR2 (0.43) FPR2FPR1F2F10PRSS1
SCHEMBL30133740 1.00 FPR2 (0.43) FPR2FPR1F2F10PRSS1
SCHEMBL28377662 1.00 FPR2 (0.43) FPR2FPR1F2F10PRSS1
SCHEMBL18964489 0.88 DGAT1 (0.46) FPR2FPR1F2F10PRSS1
SCHEMBL22179924 0.88 FPR2 (0.45) FPR2FPR1
SCHEMBL18291719 0.88 FPR2 (0.43) FPR2FPR1F2F10PRSS1
SCHEMBL29462396 0.88 FPR2 (0.43) FPR2FPR1F2F10PRSS1
SCHEMBL18291706 0.85 FPR2 (0.42) FPR2FPR1F2F10PRSS1
SCHEMBL18955177 0.83 FPR2 (0.45) FPR2FPR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11530183-B2 Piperidinone formyl peptide 2 receptor and formyl peptide 1 receptor agonists BRISTOL-MYERS SQUIBB COMPANY (US) 2022-12-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11530183-B2 Piperidinone formyl peptide 2 receptor and formyl peptide 1 receptor agonists FPR1, FPR2, FPR3 FPR2 2/4885FPR1 1/4885F2 358/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.