SCHEMBL18965684

SCHEMBL18965684

Cc1cc2nc3sccc3nc2s1

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.33
ADORA2A P29274 3/20 0.32
ADORA1 P30542 1/20 0.31
NTRK1 P04629 1/20 0.31
LTK P29376 1/20 0.31
TYRO3 Q06418 1/20 0.31
NTRK2 Q16620 1/20 0.31
CLK4 Q9HAZ1 1/20 0.31
ADORA2B P29275 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18965753 0.83 TDP1 (0.38) TDP1
SCHEMBL17865293 0.78 NTRK1 (0.37) ADORA2AADORA1NTRK1LTKTYRO3
SCHEMBL18909176 0.77 NTRK1 (0.36) ADORA2AADORA1NTRK1LTKTYRO3
SCHEMBL19303455 0.77
SCHEMBL17339845 0.77 ALDH1A1 (0.36) TDP1
SCHEMBL21610583 0.77 ADORA3 (0.32) ADORA2AADORA1ADORA2B
SCHEMBL17865307 0.74
SCHEMBL15424496 0.73 NTRK1 (0.35) TDP1ADORA2AADORA1NTRK1LTK
SCHEMBL19214697 0.72 ALDH1A1 (0.34) TDP1
SCHEMBL21515189 0.72 SMN1; SMN2 (0.34) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11778893-B2 Indaceno derivatives as organic semiconductors CLAP CO., LTD. (KR) 2023-10-03 US disclosed
US-11667650-B2 Thieno-indeno-monomers and polymers CLAP CO., LTD. (KR) 2023-06-06 US disclosed
US-20220041617-A1 THIENO-INDENO-MONOMERS AND POLYMERS BASF SE (DE) 2022-02-10 US disclosed
US-11225489-B2 Thieno-indeno-monomers and polymers BASF SE (DE) 2022-01-18 US disclosed
US-20210384434-A1 INDACENO DERIVATIVES AS ORGANIC SEMICONDUCTORS CLAP CO., LTD. (KR) 2021-12-09 US disclosed
US-10793668-B2 Naphthoindacenodithiophenes and polymers CLAP CO., LTD. (KR) 2020-10-06 US disclosed
WO-2020078815-A1 INDACENO DERIVATIVES AS ORGANIC SEMICONDUCTORS BASF SE (DE) 2020-04-23 WO disclosed
US-10388881-B2 Sorting of carbon nanotubes BASF SE (DE) 2019-08-20 US disclosed
WO-2018104367-A2 THIENO-INDENO-MONOMERS AND POLYMERS BASF SE (DE) 2018-06-14 WO disclosed
US-20170365791-A1 HETEROAROMATIC COMPOUNDS FOR ORGANIC ELECTRONICS BASF SE (DE) 2017-12-21 US disclosed
US-20170229657-A1 SORTING OF CARBON NANOTUBES CLAP CO., LTD. (KR) 2017-08-10 US disclosed
WO-2017097924-A1 NAPHTHOINDACENODITHIOPHENES AND POLYMERS BASF SE (DE) 2017-06-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11667650-B2 Thieno-indeno-monomers and polymers RPS21, OXER1, OXSR1 TDP1 2729/4885ADORA2A 1761/4885ADORA1 838/4885
US-20210384434-A1 INDACENO DERIVATIVES AS ORGANIC SEMICONDUCTORS IPO11, CYP1B1, IDO1 TDP1 1644/4885ADORA2A 3715/4885ADORA1 2640/4885
US-20170365791-A1 HETEROAROMATIC COMPOUNDS FOR ORGANIC ELECTRONICS OR10J3, NR0B1, NR0B2 TDP1 4545/4885ADORA2A 379/4885ADORA1 246/4885
US-10793668-B2 Naphthoindacenodithiophenes and polymers RPS21, NR2C2, NR0B2 TDP1 2741/4885ADORA2A 3494/4885ADORA1 2191/4885
US-20220041617-A1 THIENO-INDENO-MONOMERS AND POLYMERS RPS21, OXER1, OXSR1 TDP1 2729/4885ADORA2A 1761/4885ADORA1 838/4885
US-11225489-B2 Thieno-indeno-monomers and polymers TERT, TERB1, TERF2 TDP1 1006/4885ADORA2A 1788/4885ADORA1 2052/4885
US-11778893-B2 Indaceno derivatives as organic semiconductors IPO11, CYP1B1, IDO1 TDP1 1644/4885ADORA2A 3715/4885ADORA1 2640/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.