SCHEMBL241601

SCHEMBL241601

Cc1ccc(OC(=O)CC(=O)Oc2ccc(C)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.61
GAA P10253 2/20 0.59
KMT2A Q03164 4/20 0.57
ALDH1A1 P00352 3/20 0.57
MAPT P10636 1/20 0.57
HTT P42858 1/20 0.57
HSD17B10 Q99714 1/20 0.57
L3MBTL1 Q9Y468 3/20 0.51
TDP1 Q9NUW8 2/20 0.51
NPC1 O15118 1/20 0.51
MEN1 O00255 1/20 0.51
ESR1 P03372 1/20 0.47
RECQL P46063 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
HIF1A Q16665 1/20 0.47
MMP13 P45452 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13626251 0.94 LMNA (0.62) LMNAGAAKMT2AALDH1A1MAPT
SCHEMBL13626199 0.92 ALDH1A1 (0.56) LMNAGAAKMT2AALDH1A1MAPT
SCHEMBL10907507 0.90 LMNA (0.61) LMNAGAAKMT2AALDH1A1MAPT
SCHEMBL12722287 0.89 LMNA (0.56) LMNAGAAKMT2AALDH1A1MAPT
SCHEMBL12722233 0.89 LMNA (0.56) LMNAGAAKMT2AALDH1A1MAPT
SCHEMBL18969717 0.87 LMNA (0.49) LMNAGAAKMT2AALDH1A1MAPT
SCHEMBL18295376 0.87 LMNA (0.49) LMNAGAAKMT2AALDH1A1MAPT
SCHEMBL645265 0.86 KMT2A (0.69) LMNAGAAKMT2AALDH1A1MAPT
SCHEMBL15763957 0.86 KIF11 (0.50) LMNAGAAKMT2AALDH1A1MAPT
SCHEMBL13417357 0.86 KMT2A (0.53) LMNAGAAKMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240019738-A1 DISPLAY DEVICE AND MANUFACTURING METHOD THEREOF JAPAN DISPLAY INC. (JP) 2024-01-18 US disclosed
CN-110914334-A Polyester copolymer 阿凡田知识中心有限公司 2020-03-24 CN disclosed
WO-2018160911-A1 SUSTAINABLE, ENERGY-CURABLE POLYESTER POLYOLS AND COATINGS OR RIGID FOAMS THEREFROM RESINATE MATERIALS GROUP, INC. (US) 2018-09-07 WO disclosed
US-10011772-B2 Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal display device NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-07-03 US disclosed
US-9976086-B2 Liquid crystal aligning agent containing polyimide precursor having thermally-leaving group and/or polyimide NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-05-22 US disclosed
US-20160264867-A1 LIQUID CRYSTAL ALIGNING AGENT CONTAINING POLYIMIDE PRECURSOR HAVING THERMALLY-LEAVING GROUP AND/OR POLYIMIDE NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2016-09-15 US disclosed
US-20160244673-A1 LIQUID CRYSTAL ALIGNING AGENT, LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY DEVICE NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2016-08-25 US disclosed
US-9303176-B2 Hot melt ink composition, method for preparing a hot melt ink composition and use of a hot melt ink composition OCE-TECHNOLOGIES B.V. (NL) 2016-04-05 US disclosed
CN-101878309-B Malonate decarboxylases for industrial applications BASF SE (DE) 2016-01-13 CN disclosed
US-20150124030-A1 HOT MELT INK COMPOSITION, METHOD FOR PREPARING A HOT MELT INK COMPOSITION AND USE OF A HOT MELT INK COMPOSITION OCE-TECHNOLOGIES B.V. (NL) 2015-05-07 US disclosed
US-8901353-B2 Polyimide precursor, polyimide, and liquid crystal aligning agent NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-12-02 US disclosed
US-8859803-B2 Process for production of ketomalonic acid compounds or hydrates thereof IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 2014-10-14 US disclosed
US-8829153-B2 Polyimide precursor composition containing polyamic acid alkyl ester NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-09-09 US disclosed
EP-2447243-A1 PROCESS FOR PRODUCTION OF KETOMALONIC ACID COMPOUNDS OR HYDRATES THEREOF Ihara Chemical Industry Co., Ltd. (JP) 2012-05-02 EP disclosed
US-20120101236-A1 POLYIMIDE PRECURSOR COMPOSITION CONTAINING POLYAMIC ACID ALKYL ESTER NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-04-26 US disclosed
US-20120088888-A1 POLYIMIDE PRECURSOR, POLYIMIDE, AND LIQUID CRYSTAL ALIGNING AGENT NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-04-12 US disclosed
US-20120088888-A1 POLYIMIDE PRECURSOR, POLYIMIDE, AND LIQUID CRYSTAL ALIGNING AGENT NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-04-12 US disclosed
US-20120004443-A1 PROCESS FOR PRODUCTION OF KETOMALONIC ACID COMPOUNDS OR HYDRATES THEREOF IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 2012-01-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120004443-A1 PROCESS FOR PRODUCTION OF KETOMALONIC ACID COMPOUNDS OR HYDRATES THEREOF ME1, CA6, ME3 LMNA 4430/4885GAA 240/4885KMT2A 683/4885
US-20120088888-A1 POLYIMIDE PRECURSOR, POLYIMIDE, AND LIQUID CRYSTAL ALIGNING AGENT PUF60, F13A1, F12 LMNA 329/4885GAA 4561/4885KMT2A 380/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.