Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | RGS12 | O14924 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6560422 | 0.91 | LMNA (0.43) | LMNAADRA2CKDM4EADRA2AHIF1A | |
| SCHEMBL7958881 | 0.84 | THRB (0.53) | LMNAADRA2CKDM4EADRA2AHIF1A | |
| SCHEMBL6558895 | 0.84 | THRB (0.53) | LMNAADRA2CKDM4EADRA2AHIF1A | |
| SCHEMBL9619659 | 0.82 | LMNA (0.43) | LMNAADRA2CKDM4EADRA2AHIF1A | |
| SCHEMBL892810 | 0.80 | THRB (0.44) | LMNAADRA2CKDM4EADRA2AHIF1A | |
| SCHEMBL4901518 | 0.79 | LMNA (0.43) | LMNAADRA2CKDM4EADRA2AHIF1A | |
| SCHEMBL6558526 | 0.79 | SLC6A4 (0.43) | LMNAADRA2CKDM4EADRA2AHIF1A | |
| SCHEMBL6558951 | 0.79 | LMNA (0.47) | LMNAADRA2CKDM4EADRA2AHIF1A | |
| SCHEMBL9842268 | 0.78 | LMNA (0.48) | LMNAADRA2CKDM4EADRA2AHIF1A | |
| SCHEMBL11312359 | 0.77 | ALDH1A1 (0.36) | KDM4EHIF1AALDH1A1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250282958-A1 | Curable Photochromic Composition Including a Segmented Polymer | TRANSITIONS OPTICAL, LTD. (IE) | 2025-09-11 | — | — | US | disclosed |
| EP-4562458-A1 | CURABLE PHOTOCHROMIC COMPOSITIONS INCLUDING HYDRAZIDE AND CARBONYL FUNCTIONAL COMPONENTS | Transitions Optical, Ltd. (IE) | 2025-06-04 | — | — | EP | disclosed |
| CN-119895299-A | Curable photochromic compositions comprising a hydrazide and a carbonyl functional component | 全视线光学有限公司 | 2025-04-25 | — | — | CN | disclosed |
| EP-4514918-A1 | CURABLE PHOTOCHROMIC COMPOSITION INCLUDING A SEGMENTED POLYMER | Transitions Optical, Ltd. (IE) | 2025-03-05 | — | — | EP | disclosed |
| CN-119137238-A | Curable photochromic composition comprising segmented polymer | 光学转变有限公司 | 2024-12-13 | — | — | CN | disclosed |
| WO-2024022586-A1 | CURABLE PHOTOCHROMIC COMPOSITIONS INCLUDING HYDRAZIDE AND CARBONYL FUNCTIONAL COMPONENTS | TRANSITIONS OPTICAL, LTD. (IE) | 2024-02-01 | — | — | WO | disclosed |
| WO-2023208357-A1 | CURABLE PHOTOCHROMIC COMPOSITION INCLUDING A SEGMENTED POLYMER | TRANSITIONS OPTICAL, LTD. (IE) | 2023-11-02 | — | — | WO | disclosed |
| EP-3986371-A1 | PRODUCT FOR DYEING KERATINOUS MATERIAL, CONTAINING AMINOSILICONE, A CHROMOPHORIC COMPOUND, PRESERVATIVE AND ETHOXYLATED FATTY ALCOHOL | Henkel AG & Co. KGaA (DE) | 2022-04-27 | — | — | EP | disclosed |
| EP-3986360-A1 | PRODUCT FOR DYEING KERATINOUS MATERIAL, CONTAINING AMINOSILICONE, A CHROMOPHORIC COMPOUND, PRESERVATIVE AND A FATTY CONSTITUENT | Henkel AG & Co. KGaA (DE) | 2022-04-27 | — | — | EP | disclosed |
| CN-113993504-A | Agent for colouring keratin materials comprising an aminopolysiloxane, a colouring compound, a preservative and an ethoxylated fatty alcohol | 汉高股份有限及两合公司 | 2022-01-28 | — | — | CN | disclosed |
| WO-2020254102-A1 | PRODUCT FOR DYEING KERATINOUS MATERIAL, CONTAINING AMINOSILICONE, A CHROMOPHORIC COMPOUND, PRESERVATIVE AND A FATTY CONSTITUENT | HENKEL AG & CO. KGAA (DE) | 2020-12-24 | — | — | WO | disclosed |
| WO-2020254008-A1 | PRODUCT FOR DYEING KERATINOUS MATERIAL, CONTAINING AMINOSILICONE, A CHROMOPHORIC COMPOUND, PRESERVATIVE AND ETHOXYLATED FATTY ALCOHOL | HENKEL AG & CO. KGAA (DE) | 2020-12-24 | — | — | WO | disclosed |
| US-10328001-B2 | Combinations of preservatives for hair dyes | HENKEL AG & CO. KGAA (DE) | 2019-06-25 | — | — | US | disclosed |
| US-9999582-B2 | Combinations of preservatives for hair colors | HENKEL AG & CO. KGAA (DE) | 2018-06-19 | — | — | US | disclosed |
| US-20170172876-A1 | COMBINATIONS OF PRESERVATIVES FOR HAIR COLORS | HENKEL AG & CO. KGAA (DE) | 2017-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170172876-A1 | COMBINATIONS OF PRESERVATIVES FOR HAIR COLORS | HTR6, HRH4, HAAO | LMNA 823/4885ADRA2C 790/4885KDM4E 190/4885 |
| US-10328001-B2 | Combinations of preservatives for hair dyes | KRT18, SORD, SUCLG1 | LMNA 1349/4885ADRA2C 2084/4885KDM4E 738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.