SCHEMBL18987124

SCHEMBL18987124

CCCCCCc1cc(CCCCCC)cc(C2(C)c3ccccc3-c3ccc(-c4ncc(-c5nc(-c6ccc(C(C)(C)C)cc6)nc(-c6ccc(C(C)(C)C)cc6)n5)c5ccccc45)cc32)c1

nearest known ligand 0.32

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.32
TP53 P04637 1/20 0.32
ADORA3 P0DMS8 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
USP2 O75604 1/20 0.31
ALDH1A1 P00352 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
RAB9A P51151 1/20 0.31
KMT2A Q03164 1/20 0.31
HSD17B10 Q99714 1/20 0.31
TRPV1 Q8NER1 4/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19001624 0.95 ADORA3 (0.31) SMN1; SMN2TP53ADORA3
SCHEMBL20615191 0.84 ABCG2 (0.32) SMN1; SMN2TP53MEN1RAB9AKMT2A
SCHEMBL18216927 0.82 RAB9A (0.33) SMN1; SMN2TP53ADORA3KDM4EMEN1
SCHEMBL18987035 0.82 HSD11B1 (0.33) SMN1; SMN2KDM4EMEN1USP2ALDH1A1
SCHEMBL18987115 0.78 LPL (0.37)
SCHEMBL19001597 0.78 HSD11B1 (0.33) SMN1; SMN2MAPTRAB9A
SCHEMBL18987135 0.77 ADORA3 (0.35) SMN1; SMN2TP53ADORA3KDM4EMEN1
SCHEMBL19001626 0.74 LPL (0.35)
SCHEMBL19006916 0.73 ADORA3 (0.34) SMN1; SMN2TP53ADORA3ALDH1A1MAPT
SCHEMBL17486123 0.72 TP53 (0.36) SMN1; SMN2TP53KDM4EMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11214585-B2 Light-emitting composition CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2022-01-04 US disclosed
EP-3390418-B1 LIGHT-EMITTING COMPOUND CAMBRIDGE DISPLAY TECH LTD (GB) 2020-08-05 EP disclosed
US-20190002488-A1 LIGHT-EMITTING COMPOUND CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2019-01-03 US disclosed
US-20190002629-A1 LIGHT-EMITTING COMPOSITION CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2019-01-03 US disclosed
EP-3390418-A1 LIGHT-EMITTING COMPOUND Cambridge Display Technology Limited (GB) 2018-10-24 EP disclosed
EP-3390419-A1 LIGHT-EMITTING COMPOSITION Cambridge Display Technology Limited (GB) 2018-10-24 EP disclosed
WO-2017103584-A1 LIGHT-EMITTING COMPOUND CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2017-06-22 WO disclosed
WO-2017103584-A1 LIGHT-EMITTING COMPOUND CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2017-06-22 WO disclosed
WO-2017103586-A1 LIGHT-EMITTING COMPOSITION CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2017-06-22 WO disclosed
WO-2017103586-A1 LIGHT-EMITTING COMPOSITION CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2017-06-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11214585-B2 Light-emitting composition CRY1, CRY2, ARL1 SMN1; SMN2 2193/4885TP53 3983/4885ADORA3 963/4885
US-20190002488-A1 LIGHT-EMITTING COMPOUND AR, ARL1, IK SMN1; SMN2 3472/4885TP53 3790/4885ADORA3 429/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.