SCHEMBL190002

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL188944	0.85	SMN1; SMN2 (0.60)	MAOBGABRA1GABRB2MAPTRAB9A
	SCHEMBL189840	0.85	RAB9A (0.59)	MAPTRAB9AL3MBTL1NPC1SMN1; SMN2
	SCHEMBL190218	0.84	PARP10 (0.49)	MAOBMAPTRAB9AL3MBTL1NPC1
	SCHEMBL253621	0.84	MAOB (0.55)	MAOBMAOAMAPTRAB9AL3MBTL1
	SCHEMBL189690	0.84	RAB9A (0.54)	MAOBMAOAMAPTRAB9AL3MBTL1
	SCHEMBL189485	0.84	RAB9A (0.50)	MAOBMAPTRAB9AL3MBTL1NPC1
	SCHEMBL189765	0.82	RAB9A (0.46)	MAOBMAOAMAPTRAB9AL3MBTL1
	SCHEMBL189486	0.82	MAOB (0.57)	MAOBMAPTRAB9AL3MBTL1NPC1
	SCHEMBL189410	0.81	RAB9A (0.51)	MAPTRAB9AL3MBTL1NPC1SMN1; SMN2
	SCHEMBL189525	0.81	RAB9A (0.60)	MAPTRAB9AL3MBTL1NPC1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.