SCHEMBL19001659

SCHEMBL19001659

Cc1ccccc1-c1cccc2c1c1ccccc1n2-c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.53
ATM Q13315 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
MAPT P10636 2/20 0.41
TP53 P04637 1/20 0.41
PLA2G2A P14555 1/20 0.39
CYP17A1 P05093 1/20 0.39
CYP1A2 P05177 1/20 0.39
MCL1 Q07820 1/20 0.39
BAD Q92934 1/20 0.39
BRD4 O60885 1/20 0.38
MAPK8 P45983 1/20 0.38
ALKBH5 Q6P6C2 1/20 0.38
FTO Q9C0B1 1/20 0.38
PGR P06401 1/20 0.37
MAPK1 P28482 1/20 0.37
HTT P42858 1/20 0.37
REN P00797 1/20 0.36
EGFR P00533 1/20 0.36
CDK1 P06493 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21742610 0.98 KDM4E (0.52) KDM4EATML3MBTL1MAPTTP53
SCHEMBL11998218 0.90 L3MBTL1 (0.65) KDM4EATML3MBTL1MAPTPLA2G2A
SCHEMBL21742866 0.89 KDM4E (0.49) KDM4EATML3MBTL1PLA2G2ACYP17A1
SCHEMBL18561901 0.88 L3MBTL1 (0.63) KDM4EATML3MBTL1MAPTPLA2G2A
SCHEMBL23989180 0.88 KDM4E (0.50) KDM4EATML3MBTL1MAPTPLA2G2A
SCHEMBL21742523 0.87 KDM4E (0.46) KDM4EATML3MBTL1MAPTPLA2G2A
SCHEMBL21742609 0.87 L3MBTL1 (0.46) KDM4EATML3MBTL1MAPTPLA2G2A
SCHEMBL883413 0.86 KDM4E (0.61) KDM4EATML3MBTL1MAPTPLA2G2A
SCHEMBL17877968 0.86 KDM4E (0.61) KDM4EATML3MBTL1MAPTPLA2G2A
SCHEMBL19011066 0.84 KDM4E (0.44) KDM4EATML3MBTL1MAPTPLA2G2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024126322-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2024-06-20 WO disclosed
WO-2024013275-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2024-01-18 WO disclosed
WO-2024013276-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2024-01-18 WO disclosed
CN-117229197-A Carbazole derivative with AEE characteristic and preparation method and application thereof 辽宁师范大学 2023-12-15 CN disclosed
EP-3935129-B1 LIGANDS FOR NANO-SIZED MATERIALS MERCK PATENT GMBH (DE) 2023-11-29 EP disclosed
US-11832513-B2 Materials for electronic devices MERCK PATENT GMBH (DE) 2023-11-28 US disclosed
US-11832513-B2 Materials for electronic devices MERCK PATENT GMBH (DE) 2023-11-28 US disclosed
US-20230373941-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-11-23 US disclosed
US-20230373941-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-11-23 US disclosed
US-20230329092-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-10-12 US disclosed
WO-2019101719-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2019-05-31 WO disclosed
WO-2019048443-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2019-03-14 WO disclosed
WO-2019048458-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2019-03-14 WO disclosed
US-20190040034-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2019-02-07 US disclosed
WO-2019020654-A1 SPIROBIFLUORENE DERIVATIVES FOR USE IN ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2019-01-31 WO disclosed
WO-2018087020-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2018-05-17 WO disclosed
WO-2017144150-A2 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2017-08-31 WO disclosed
WO-2017133829-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2017-08-10 WO disclosed
WO-2017102064-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2017-06-22 WO disclosed
WO-2017102063-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2017-06-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11832513-B2 Materials for electronic devices PNMT, DDT, COMT KDM4E 3302/4885ATM 1537/4885L3MBTL1 3148/4885
US-20190040034-A1 MATERIALS FOR ELECTRONIC DEVICES EFNA1, GPX1, EPX KDM4E 3365/4885ATM 2413/4885L3MBTL1 4115/4885
US-20230373941-A1 COMPOUNDS FOR ELECTRONIC DEVICES CYP2E1, GPX1, ERCC1 KDM4E 2854/4885ATM 3499/4885L3MBTL1 3395/4885
US-20230329092-A1 MATERIALS FOR ELECTRONIC DEVICES SOD1, GPX1, EFNA1 KDM4E 2946/4885ATM 2113/4885L3MBTL1 4497/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.