Sugi Predict

Sugi Predict / Compounds / SCHEMBL19001972

SCHEMBL19001972

SCHEMBL19001972

c1ccc(-c2ccc(N(c3ccc(-c4ccccc4)cc3)c3ccc4c(c3)-c3ccccc3C43c4ccccc4-c4cc(-c5ccccc5)ccc43)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PDK2 Q15119 11/20 0.41
▸ MAPT P10636 3/20 0.38
▸ L3MBTL1 Q9Y468 2/20 0.38
▸ MEN1 O00255 2/20 0.38
▸ LMNA P02545 2/20 0.38
▸ KMT2A Q03164 2/20 0.38
▸ SMN1; SMN2 Q16637 2/20 0.38
▸ THRB P10828 2/20 0.38
▸ APAF1 O14727 1/20 0.38
▸ NPC1 O15118 1/20 0.38
▸ XBP1 P17861 1/20 0.38
▸ PTBP1 P26599 1/20 0.38
▸ HTT P42858 1/20 0.38
▸ RAB9A P51151 1/20 0.38
▸ GALK1 P51570 1/20 0.38
▸ BLM P54132 1/20 0.38
▸ SMAD3 P84022 1/20 0.38
▸ ATM Q13315 1/20 0.38
▸ NPSR1 Q6W5P4 1/20 0.38
▸ KDM4E B2RXH2 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24646771 0.98 PDK2 (0.40) PDK2MAPTL3MBTL1MEN1LMNA
SCHEMBL15892441 0.97 PDK2 (0.40) PDK2MAPTL3MBTL1MEN1LMNA
SCHEMBL15892440 0.97 PDK2 (0.40) PDK2MAPTL3MBTL1MEN1LMNA
SCHEMBL15213628 0.97 PDK2 (0.40) PDK2MAPTL3MBTL1MEN1LMNA
SCHEMBL24750938 0.97 PDK2 (0.40) PDK2MAPTL3MBTL1MEN1LMNA
SCHEMBL16544732 0.97 PDK2 (0.40) PDK2MAPTL3MBTL1MEN1LMNA
SCHEMBL24647085 0.97 PDK2 (0.40) PDK2MAPTL3MBTL1MEN1LMNA
SCHEMBL23449414 0.97 PDK2 (0.40) PDK2MAPTL3MBTL1MEN1LMNA
SCHEMBL22425411 0.97 PDK2 (0.40) PDK2MAPTL3MBTL1MEN1LMNA
SCHEMBL15213737 0.97 PDK2 (0.43) PDK2MAPTL3MBTL1MEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230225196-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-07-13 — — US disclosed
US-20230225196-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-07-13 — — US disclosed
WO-2023099430-A1 TRIPHENYLENE-TRIAZINE-DIBENZOFURAN/DIBENZOTHIOPHENE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2023-06-08 — — WO disclosed
EP-4186898-A1 COMPOSITION FOR ORGANIC ELECTRONIC COMPOUNDS Merck Patent GmbH (DE) 2023-05-31 — — EP disclosed
US-20230159434-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-05-25 — — US disclosed
US-20230159434-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-05-25 — — US disclosed
US-20230150987-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-05-18 — — US disclosed
US-20230150987-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-05-18 — — US disclosed
US-20230138100-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-05-04 — — US disclosed
US-20230138100-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-05-04 — — US disclosed
WO-2020225069-A1 ELECTRONIC DEVICE MERCK PATENT GMBH (DE) 2020-11-12 — — WO disclosed
US-20200283386-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2020-09-10 — — US disclosed
US-20200231578-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2020-07-23 — — US disclosed
WO-2020127145-A2 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2020-06-25 — — WO disclosed
WO-2020109434-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2020-06-04 — — WO disclosed
WO-2020109269-A1 ELECTRONIC DEVICE MERCK PATENT GMBH (DE) 2020-06-04 — — WO disclosed
WO-2020108899-A1 ELECTRONIC DEVICE MERCK PATENT GMBH (DE) 2020-06-04 — — WO disclosed
US-20200055822-A1 MATERIALS FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2020-02-20 — — US disclosed
WO-2019048443-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2019-03-14 — — WO disclosed
WO-2017102063-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2017-06-22 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230150987-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES SLCO2B1, SLCO2A1, SLCO1B3 PDK2 2425/4885MAPT 1187/4885L3MBTL1 3258/4885
US-20200283386-A1 MATERIALS FOR ELECTRONIC DEVICES EFNA1, GPX1, SOD1 PDK2 461/4885MAPT 3032/4885L3MBTL1 4544/4885
US-20200055822-A1 MATERIALS FOR ORGANIC ELECTRONIC DEVICES PNMT, DDT, TYR PDK2 602/4885MAPT 2103/4885L3MBTL1 2878/4885
US-20230138100-A1 COMPOUNDS FOR ELECTRONIC DEVICES CYP2C19, ETV6, ESR1 PDK2 611/4885MAPT 2915/4885L3MBTL1 4354/4885
US-20230159434-A1 MATERIALS FOR ELECTRONIC DEVICES OCIAD2, AOC2, OCIAD1 PDK2 741/4885MAPT 731/4885L3MBTL1 2527/4885
US-20200231578-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES SLCO2B1, SLCO2A1, SLCO1B3 PDK2 2425/4885MAPT 1187/4885L3MBTL1 3258/4885
US-20230225196-A1 MATERIALS FOR ELECTRONIC DEVICES SELE, EPHA6, EPX PDK2 1021/4885MAPT 3046/4885L3MBTL1 2697/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.