Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 7/20 | 0.62 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.60 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.59 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.59 |
| ▸ | MPO | P05164 | 4/20 | 0.59 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.59 |
| ▸ | YAP1 | P46937 | 1/20 | 0.57 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.57 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.57 |
| ▸ | AURKA | O14965 | 1/20 | 0.57 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.57 |
| ▸ | FABP4 | P15090 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Flufenamic Acid SCHEMBL17497 | 0.89 | RXFP1 (0.75) | TAS2R14RXFP1AKR1C3AKR1C2PTGS1 | |
| Flufenamic Acid SCHEMBL29356958 | 0.89 | RXFP1 (0.75) | TAS2R14RXFP1AKR1C3AKR1C2PTGS1 | |
| SCHEMBL28418888 | 0.89 | FABP4 (0.59) | TAS2R14RXFP1AKR1C3AKR1C2PTGS1 | |
| SCHEMBL30059145 | 0.89 | FABP4 (0.59) | TAS2R14RXFP1AKR1C3AKR1C2PTGS1 | |
| Flufenamic Acid SCHEMBL9845499 | 0.87 | RXFP1 (0.73) | TAS2R14RXFP1AKR1C3AKR1C2PTGS1 | |
| Flufenamic Acid SCHEMBL11524554 | 0.87 | RXFP1 (0.73) | TAS2R14RXFP1AKR1C3AKR1C2PTGS1 | |
| SCHEMBL8416271 | 0.82 | RXFP1 (0.81) | RXFP1MPOGRIK1 | |
| Flufenamic Acid SCHEMBL10531046 | 0.81 | MPO (0.67) | TAS2R14RXFP1AKR1C3AKR1C2PTGS1 | |
| SCHEMBL16088591 | 0.81 | ALDH1A1 (0.63) | RXFP1PTGS1GRIK1 | |
| SCHEMBL26735295 | 0.81 | RXFP1 (0.64) | TAS2R14RXFP1AKR1C3AKR1C2MPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102605-A1 | PHARMACEUTICAL PREPARATIONS | ANALYTICON DISCOVERY GMBH (DE) | 2017-06-22 | — | — | WO | disclosed |