Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13192695 | 0.80 | PARP1 (0.50) | GABRA1GABRB2LMNAGABRG2GABRB3 | |
| SCHEMBL24995382 | 0.80 | HSD17B10 (0.49) | GABRA1GABRB2LMNAGABRG2GABRB3 | |
| SCHEMBL9305449 | 0.79 | LMNA (0.38) | GABRA1GABRB2LMNAGABRG2GABRB3 | |
| SCHEMBL8713612 | 0.79 | LMNA (0.38) | GABRA1GABRB2LMNAGABRG2GABRB3 | |
| SCHEMBL1128920 | 0.79 | NPC1 (0.46) | GABRA1GABRB2LMNAGABRG2GABRB3 | |
| SCHEMBL20315207 | 0.79 | NUDT1 (0.47) | GABRA1GABRB2LMNAGABRG2GABRB3 | |
| SCHEMBL21888908 | 0.78 | GABRA1 (0.46) | GABRA1GABRB2LMNAGABRG2GABRB3 | |
| SCHEMBL19002275 | 0.76 | L3MBTL1 (0.51) | GABRA1GABRB2LMNAGABRG2GABRB3 | |
| SCHEMBL8956217 | 0.76 | PSMD14 (0.39) | HPGDPARP1MGAMGAASI | |
| SCHEMBL6139625 | 0.76 | MGAM (0.60) | MGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017106552-A1 | POTENTIATORS OF BETA-LACTAM ANTIBIOTICS AND COMBINATION THERAPY | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2017-06-22 | — | — | WO | disclosed |