Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.30 |
| ▸ | BRD1 | O95696 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26834607 | 0.83 | MAPT (0.32) | LMNA | |
| SCHEMBL5781980 | 0.77 | LPL (0.46) | CA12CA1CA2CA7CA14 | |
| SCHEMBL24135395 | 0.77 | CASP1 (0.41) | CYP11B1CYP11B2 | |
| SCHEMBL22202029 | 0.77 | DRD2 (0.41) | ALDH1A1LMNAHTTSMN1; SMN2CA12 | |
| SCHEMBL21433623 | 0.77 | ALDH1A1 (0.41) | ALDH1A1LMNAHTTSMN1; SMN2KDM4E | |
| SCHEMBL19152920 | 0.74 | PGR (0.39) | ALDH1A1LMNAHTTSMN1; SMN2KDM4E | |
| SCHEMBL25894591 | 0.74 | ALDH1A1 (0.35) | ALDH1A1LMNAHTTSMN1; SMN2KDM4E | |
| SCHEMBL30284869 | 0.73 | LPL (0.44) | CA12CA1CA2CA7CA14 | |
| SCHEMBL4158988 | 0.73 | LPL (0.44) | CA12CA1CA2CA7CA14 | |
| SCHEMBL23635245 | 0.72 | LPL (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2906539-B1 | INHIBITORS OF VIRAL REPLICATION, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES | HIVIH (FR) | 2017-06-21 | — | — | EP | disclosed |