Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19003274 | 0.85 | MMP1 (0.58) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL19003307 | 0.81 | EGFR (0.60) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL18985271 | 0.81 | CA12 (0.54) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL19003250 | 0.80 | MAPT (0.51) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL18985197 | 0.80 | MEN1 (0.55) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL27731432 | 0.80 | ALDH1A1 (0.62) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL19003313 | 0.79 | SAE1 (0.46) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL19003257 | 0.78 | KDM4E (0.49) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL19003248 | 0.78 | LMNA (0.56) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL19003253 | 0.77 | MAOB (0.56) | MAPTLMNAMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102014-A1 | PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE | UNIVERSITE D'AIX-MARSEILLE (FR) | 2017-06-22 | — | — | WO | disclosed |